脑脊液细胞学诊断颅内胚胎性癌：一例报告
Diagnosis of intracranial embryonal carcinoma by cerebrospinal fluid cytology: a case report.
作者信息
Bi Xizhuang, Zhao Dachun, He Qiaowei, Liu Fengjie, Gong Li, Li Hua
机构信息
Department of Neurology, Qingdao University Affiliated Yantai Yuhuangding Hospital Qingdao, China.
Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing, China.
出版信息
Int J Clin Exp Pathol. 2020 May 1;13(5):1216-1219. eCollection 2020.
BACKGROUND
The incidence of primary intracranial germ cell tumors (GCTs) is relatively low comparing to other ones. Embryonal carcinoma (EC) is an especially rare subtype and the diagnosis presents to be a challenge. Few cases have been reported.
CASE PRESENTATION
We report a case of intracranial EC located in the temporal lobe with malignant tumor cells occasionally detected by the cytology of cerebrospinal fluid (CSF). The pathology confirmed the diagnosis after the patient underwent tumor resection.
CONCLUSION
This is the first report about one case of intracranial primary EC located in the temporal lobe. It is also the first report of tumor cells of EC detected in the CSF.
背景
与其他原发性颅内生殖细胞肿瘤（GCTs）相比，原发性颅内生殖细胞肿瘤的发病率相对较低。胚胎癌（EC）是一种特别罕见的亚型，其诊断颇具挑战性。鲜有病例报道。
病例介绍
我们报告一例位于颞叶的颅内胚胎癌病例，脑脊液（CSF）细胞学检查偶尔检测到恶性肿瘤细胞。患者接受肿瘤切除术后，病理确诊。
结论
这是首例关于位于颞叶的颅内原发性胚胎癌的报告。也是在脑脊液中检测到胚胎癌细胞的首例报告。
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