Chernozub Andrii, Potop Vladimir, Korobeynikov Georgiy, Timnea Olivia Carmen, Dubachinskiy Oleg, Ikkert Oksana, Briskin Yuriy, Boretsky Yuriy, Korobeynikova Lesia
Petro Mohyla Black Sea State University, Mykolaiv, Ukraine.
Faculty of Physical Education and Sport, Ecological University of Bucharest, Bucharest, Romania.
PeerJ. 2020 May 22;8:e9137. doi: 10.7717/peerj.9137. eCollection 2020.
To study the peculiarities of changes in creatinine concentration in blood serum of untrained men during the prolonged usage of training loads different in volume and intensity, and to determine the value of this biochemical marker for the assessment of adaptive body changes during fitness training.
We examined 50 untrained men aged 18-20 years who had no contraindications for practicing fitness. Taking into account the aim of the research, we divided these people into two groups: group A and group B. The research participants used training load regimes different in volume and intensity: representatives of group Aused low intensity training load regime ( = 0.53) and representatives of group B used high intensity training load regime ( = 0.72). To assess the adaptive body changes in the examined contingent, we used the anthropometry method (circumference body size) and bioimpedansometry (body composition indicators). We also determined the features of adaptation-compensatory body reactions to different training loads by means of biochemical control of creatinine concentration in blood serum.
The obtained results showed a significant increase in basal level of creatinine concentration in blood serum (by 17.6%) of group B representatives fixed after 3 months of practicing fitness in high intensity training load regime ( = 0.72). This group representative also revealed the most pronounced manifestation of adaptive body changes confirmed by the results of the maximal muscle strength growth () and circumference body size, which was almost 2.5 times higher than the results of group A representatives for the same period of time. The parameters indicating the load volume in a set () were almost 62.0 % higher in group A representatives in comparison with group B during all stages of control. Nonetheless, the highest creatinine concentration in blood serum (by 11.1 % ( < 0.05) was fixed in group A representatives in response to training load after 3 months of practicing. This fact testifies to the important role of the creatine phosphokinase mechanism of energy supply of muscular activity in the conditions of high volume and low intensity training load regime ( = 0.53).
The analysis of the results obtained during a series of experimental studies indicates the need and feasibility of using the indicator of basal level of creatinine concentration in blood during fitness training, especially in the conditions of high intensity and low volume training load regime ( = 0.72), as an informative marker for assessing the process of long-term adaptation.
研究未受过训练的男性在长时间使用不同体积和强度的训练负荷时血清肌酐浓度变化的特点,并确定该生化指标在评估健身训练期间身体适应性变化中的价值。
我们检查了50名年龄在18 - 20岁、无健身禁忌的未受过训练的男性。考虑到研究目的,我们将这些人分为两组:A组和B组。研究参与者采用了不同体积和强度的训练负荷方案:A组代表采用低强度训练负荷方案(= 0.53),B组代表采用高强度训练负荷方案(= 0.72)。为了评估受试人群的身体适应性变化,我们采用了人体测量法(身体周长尺寸)和生物电阻抗分析法(身体成分指标)。我们还通过对血清肌酐浓度的生化检测来确定身体对不同训练负荷的适应 - 代偿反应特征。
所得结果显示,在高强度训练负荷方案(= 0.72)下进行3个月健身训练后,B组代表血清肌酐浓度的基础水平显著升高(升高了17.6%)。该组代表还表现出最明显的身体适应性变化,这通过最大肌肉力量增长()和身体周长尺寸的结果得到证实,该结果比同期A组代表的结果高出近2.5倍。在所有对照阶段,A组代表中表示一组训练负荷量的参数()比B组高出近62.0%。尽管如此,在进行3个月训练后,A组代表在对训练负荷的反应中血清肌酐浓度最高(升高了11.1%(< 0.05))。这一事实证明了在高训练量和低强度训练负荷方案(= 0.53)条件下,肌酸磷酸激酶肌肉活动能量供应机制的重要作用。
对一系列实验研究所得结果的分析表明,在健身训练期间,尤其是在高强度和低训练量负荷方案(= 0.72)的条件下,使用血清肌酐浓度基础水平指标作为评估长期适应过程的信息性标志物是必要且可行的。