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伴有脾脓肿破裂的全身性类鼻疽病

Systemic Melioidosis With Ruptured Splenic Abscess.

作者信息

Chinnakkulam Kandhasamy Sakthivel, Elamurugan T P, Naik Debasis, Rohith Gorrepati, Nelamangala Ramakrishnaiah Vishnu Prasad

机构信息

Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, IND.

General Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, IND.

出版信息

Cureus. 2020 May 4;12(5):e7956. doi: 10.7759/cureus.7956.

Abstract

Melioidosis is a severe systemic disease caused by the bacterium , commonly found in soil, ground water, and ponds of endemic regions. It is transmitted to humans via percutaneous inoculation while working in these areas without protective clothing and footwear giving rise to the disease which has a high case fatality rate. It has a wide range of clinical manifestations, varying from asymptomatic infection to localized abscess formation to fulminating disease with multiple organ involvement and even death. Currently, there are no known pathognomonic features or specific criteria which can lead to a confident diagnosis of melioidosis. The gold standard diagnostic test is culture sensitivity of blood, pus, or bodily fluids, which itself has a low sensitivity. Imaging findings are not specific and can mimic other bacterial infection. However, awareness of these radiographic manifestations in multiple organs can raise the possibility of diagnosis and lead to more early proper treatment and thereby lower the high mortality associated with this disease. We here present a rare case of systemic melioidosis with ruptured splenic abscess managed laboriously with antibiotics and splenectomy and wish to review the literature.

摘要

类鼻疽是一种由细菌引起的严重全身性疾病,常见于流行地区的土壤、地下水和池塘中。在这些地区工作时,如果没有防护服和防护鞋,通过经皮接种可将其传播给人类,从而引发具有高病死率的疾病。它有广泛的临床表现,从无症状感染到局部脓肿形成,再到累及多个器官的暴发性疾病甚至死亡。目前,尚无已知的特征性表现或特定标准能够确诊类鼻疽。金标准诊断测试是对血液、脓液或体液进行培养敏感性检测,而其本身敏感性较低。影像学表现不具有特异性,可与其他细菌感染相似。然而,了解多个器官的这些影像学表现可提高诊断的可能性,并导致更早期的恰当治疗,从而降低与该疾病相关的高死亡率。我们在此呈现一例罕见的全身性类鼻疽伴脾脓肿破裂的病例,该病例通过抗生素治疗和脾切除术艰难治愈,并希望对相关文献进行综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcf0/7270831/7f846f56e268/cureus-0012-00000007956-i01.jpg

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