Bilal Muhammad, Haseeb Abdul, Saeed Alina, Saeed Aena, Ghaffar Palwasha
Internal Medicine/Pediatrics, Dr. Ruth K. M. Pfau Civil Hospital, Karachi, PAK.
Internal Medicine, The Wright Center for Graduate Medical Education, Scranton, USA.
Cureus. 2020 May 4;12(5):e7957. doi: 10.7759/cureus.7957.
The childhood obesity epidemic has caused the global prevalence of hypertension (HTN) in children to increase from 2% to 4%. However, there is limited data regarding this issue in Pakistan. Hence this cross-sectional study aims to document the prevalence of HTN and its risk factors among children visiting the out patient department (OPD) of a government hospital in Karachi, which is one of the largest cities in Pakistan.
One thousand children aged between 4 and 12 years who visited the OPD in October 2019 were included. Blood pressures (BPs) for each child were measured manually and recorded. Their guardians were then interviewed to assess the risk factors present in each child. Data collected were analyzed using SPSS (Statistical Package for the Social Sciences).
Among all the children, those between 4 and 7 years of age had a higher prevalence of HTN (19.2%; 9.2% stage 1 and 10.0% stage 2) than children aged between 8 and 12 years (14.5%; 8.0% stage 1 and 6.5% stage 2). Obese children between the age of 4 and 7 years (OR = 3.11) were more likely to develop HTN. Moreover, children with a positive family history of HTN were 1.43 times more likely to have HTN and 1.32 times more likely to have pre-HTN. There was no significant association of gender, artificial feeding, low birth weight, and maternal smoking with HTN.
The prevalence is particularly higher in children aged between 4 and 7 years (19.2%) and there is a strong association between high BMI (body mass index), family history of HTN, and high-fat diet intake with HTN in children. There was no significant variation of prevalence between both genders.
儿童肥胖流行已导致全球儿童高血压(HTN)患病率从2%升至4%。然而,巴基斯坦关于此问题的数据有限。因此,这项横断面研究旨在记录在巴基斯坦最大城市之一卡拉奇一家政府医院门诊部(OPD)就诊的儿童中高血压及其危险因素的患病率。
纳入2019年10月到该门诊部就诊的1000名4至12岁儿童。手动测量并记录每个儿童的血压(BP)。然后对其监护人进行访谈,以评估每个儿童存在的危险因素。使用SPSS(社会科学统计软件包)对收集的数据进行分析。
在所有儿童中,4至7岁儿童的高血压患病率(19.2%;1期9.2%,2期10.0%)高于8至12岁儿童(14.5%;1期8.0%,2期6.5%)。4至7岁的肥胖儿童(OR = 3.11)患高血压的可能性更大。此外,有高血压家族史的儿童患高血压的可能性高1.43倍,患高血压前期的可能性高1.32倍。性别、人工喂养、低出生体重和母亲吸烟与高血压之间无显著关联。
4至7岁儿童的患病率尤其更高(19.2%),儿童中高体重指数(BMI)、高血压家族史和高脂肪饮食摄入与高血压之间存在密切关联。两性之间的患病率无显著差异。