儿童高血压的发病率——身体活动和久坐行为的影响：IDEFICS研究：高血压、生活方式与儿童

Incidence of high blood pressure in children - effects of physical activity and sedentary behaviors: the IDEFICS study: High blood pressure, lifestyle and children.

作者信息

de Moraes Augusto César Ferreira, Carvalho Heráclito Barbosa, Siani Alfonso, Barba Gianvincenzo, Veidebaum Toomas, Tornaritis Michael, Molnar Denes, Ahrens Wolfgang, Wirsik Norman, De Henauw Stefaan, Mårild Staffan, Lissner Lauren, Konstabel Kenn, Pitsiladis Yannis, Moreno Luis A

机构信息

School of Medicine of the University of São Paulo, FMUSP, São Paulo, Brazil; Universidad de Zaragoza, Facultad de Ciencias de la Salud, GENUD Research Group (Growth, Exercise, Nutrition and Development) Zaragoza, Spain; YCARE (Youth/Child and Cardiovascular Risk and Environmental) Research Group, FMUSP, Brazil.

School of Medicine of the University of São Paulo, FMUSP, São Paulo, Brazil; YCARE (Youth/Child and Cardiovascular Risk and Environmental) Research Group, FMUSP, Brazil.

出版信息

Int J Cardiol. 2015 Feb 1;180:165-70. doi: 10.1016/j.ijcard.2014.11.175. Epub 2014 Nov 26.

DOI:10.1016/j.ijcard.2014.11.175

PMID:25460372

Abstract

BACKGROUND/OBJECTIVES: High blood pressure (HBP) is one of the most important risk factors for cardiovascular diseases and it has a high prevalence in pediatric populations. However, the determinants of the incidence of Pre-HBP and HBP in children are not well known. i) To describe the incidence of HBP in European children; and ii) to evaluate the effect of physical activity (PA) and sedentary behavior (SB) on the Pre-HBP and HBP.

METHODS

The IDEFICS cohort study. A total of 16,228 children 2-9years at baseline were recruited by complex sampling population-based survey in eight European countries. At baseline (T0), 5221 children were selected for accelerometer measurements; 5061 children were re-examined 2years later (T1). We estimated the incidence of Pre-HBP and HBP and evaluate the effect of PA and SB on the Pre-HBP and HBP, by computing relative risks and the corresponding 95% confidence intervals (RR, 95% CI).

RESULTS

Incidences of Pre-HBP and HBP per year were: 121/1000 children and 110/1000 children, respectively. We found that children maintaining SB>2h/d during the two year follow-up showed a RR of having HBP of 1.28 (1.03-1.60). Children in T1 not performing the recommended amount of PA (<60min/d) have a RR of HBP of 1.53 (1.12 to 2.09). We found no association between pre-HBP and the behaviors.

CONCLUSION

The incidence of pre-HBP and HBP is high in European children. Maintaining sedentary behaviors during childhood increases the risk of developing HBP after two years of follow-up.

摘要

背景/目的：高血压（HBP）是心血管疾病最重要的危险因素之一，在儿童人群中患病率很高。然而，儿童前期高血压（Pre-HBP）和高血压（HBP）发病的决定因素尚不清楚。i）描述欧洲儿童高血压的发病率；ii）评估身体活动（PA）和久坐行为（SB）对儿童前期高血压和高血压的影响。

方法

IDEFICS队列研究。通过对八个欧洲国家基于人群的复杂抽样调查，共招募了16228名基线年龄为2至9岁的儿童。在基线（T0）时，选择5221名儿童进行加速度计测量；两年后（T1）对5061名儿童进行复查。通过计算相对风险和相应的95%置信区间（RR，95%CI），我们估计了儿童前期高血压和高血压的发病率，并评估了身体活动和久坐行为对儿童前期高血压和高血压的影响。

结果

儿童前期高血压和高血压的年发病率分别为：每1000名儿童中有121例和110例。我们发现，在两年随访期间每天久坐时间超过2小时的儿童患高血压的相对风险为1.28（1.03 - 1.60）。在T1时未达到推荐身体活动量（<60分钟/天）的儿童患高血压的相对风险为1.53（1.12至2.09）。我们未发现儿童前期高血压与这些行为之间存在关联。