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经输尿管镜真空辅助取石术与 MPCNL 治疗 2-4cm 肾结石的比较。

RIRS with Vacuum-Assisted Ureteral Access Sheath versus MPCNL for the Treatment of 2-4 cm Renal Stone.

机构信息

Urology, Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.

Minimally Invasive Technique and Product Translational Center, Guangzhou Medical University, Guangzhou, Guangdong, China.

出版信息

Biomed Res Int. 2020 May 14;2020:8052013. doi: 10.1155/2020/8052013. eCollection 2020.

Abstract

OBJECTIVE

Comparison of outcomes between RIRS with vacuum-assisted ureteral access sheath (V-UAS) and MPCNL in the treatment of renal stone.

MATERIALS AND METHODS

28 patients with 2-4 cm renal stone were treated using RIRS with 14/16 F V-UAS. The outcomes were compared to those who underwent MPCNL with 16 F Amplatz sheath using a matched-pair analysis in a 1 : 2 scenario. Matching criteria included stone size, location and laterality, gender, age, BMI, and degree of hydronephrosis. Patients' demographics, perioperative and postoperative characteristics, complications, stone-free rate (SFR), and auxiliary procedures were compared.

RESULTS

Mean operative times for the RIRS and MPCNL groups were 72.4 ± 21.3 minutes and 67.4 ± 25 minutes ( = 0.042). Postoperative pain was significantly less in the RIRS group. The initial SFR was 50% for the RIRS group and 73.2% for the MPCNL group ( = 0.035). The final SFR at postoperative three months improved to 89.3% for the RIRS group and 92.9% for the MPCNL group ( = 0.681). The auxiliary procedure rates were higher in the RIRS group (42.9% vs. 25%, = 0.095). The overall complication rate in the RIRS group was lower, but the significant difference was not found.

CONCLUSION

In the treatment of 2-4 cm renal stone, using V-UAS in RIRS can improve surgical efficiency with lower postoperative early pain scores. Comparing with MPCNL, its initial SFR was more depressed, and there is still a trend towards requiring more auxiliary procedures to achieve comparable final SFR.

摘要

目的

比较 RIRS 联合真空辅助输尿管镜鞘(V-UAS)与 MPCNL 治疗肾结石的疗效。

材料与方法

28 例 2-4cm 肾结石患者采用 14/16F V-UAS 行 RIRS 治疗,通过 1:2 配对分析,将其与采用 16F Amplatz 鞘行 MPCNL 的患者的结果进行比较。匹配标准包括结石大小、位置和侧别、性别、年龄、BMI 和肾积水程度。比较患者的人口统计学、围手术期和术后特征、并发症、结石清除率(SFR)和辅助手术。

结果

RIRS 组和 MPCNL 组的平均手术时间分别为 72.4±21.3 分钟和 67.4±25 分钟(=0.042)。RIRS 组术后疼痛明显较轻。RIRS 组初始 SFR 为 50%,MPCNL 组为 73.2%(=0.035)。RIRS 组术后 3 个月最终 SFR 提高至 89.3%,MPCNL 组提高至 92.9%(=0.681)。RIRS 组辅助手术率较高(42.9%比 25%,=0.095)。RIRS 组总体并发症发生率较低,但差异无统计学意义。

结论

在治疗 2-4cm 肾结石时,RIRS 联合 V-UAS 可提高手术效率,降低术后早期疼痛评分。与 MPCNL 相比,其初始 SFR 较低,仍有更多辅助手术的趋势,以达到可比的最终 SFR。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46c0/7245689/1dbc2dc27532/BMRI2020-8052013.001.jpg

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