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治疗大的下盏结石(10 - 20毫米)的创新方法:对比单纯水扩张术,评估在软性输尿管镜检查中改良T形倾斜体位和下盏水扩张技术:前瞻性随机对照研究

Innovative approaches to large lower calyceal stones (10-20 mm): evaluating modified T-tilt position and lower calyx hydrodilatation techniques in flexible ureteroscopy versus hydrodilatation alone: prospective randomized controlled study.

作者信息

Shello Haitham Abdalla, Gabril Mahmoud, Elhendawy Abdelaziz, Farahat Adel

机构信息

Zagazig University Hospital, Zagazig, Egypt.

Al Mouwasat Hospital, Riyadh, Saudi Arabia.

出版信息

Int Urol Nephrol. 2025 Jan 31. doi: 10.1007/s11255-024-04339-4.

Abstract

BACKGROUND

Managing lower calyceal stones poses significant challenges. Flexible ureteroscopy and laser lithotripsy (FURSL) are standard techniques for treating large stones (10-20 mm).

OBJECTIVE

This study evaluates the role of the T-tilt position (45-degree Trendelenburg with a 45-degree lateral tilt against the side of the stone) and hydrodilatation of the lower calyx with 50 cc saline injection as needed in optimizing stone-free rates and safety during FURSL for lower calyceal stones.

METHODS

Following ethical approval, a prospective randomized study with 197 patients was conducted. 13 patients were excluded (9 with renal anomalies or prior surgeries affecting anatomy, and four who refused participation). The remaining 184 were randomized into Group A (92 patients in T-tilt with hydrodilatation) and Group B (92 patients with hydrodilatation in lithotomy position). Randomization was achieved with computer-generated numbers stored in sealed envelopes. All patients had 10-20 mm stones and underwent FURSL using a 7.5 FR flexible ureteroscope and 200-micron Wolf laser fiber. Follow-up CT KUB was performed at 1 and 3 months, assessing stone-free status (no residual stones or residual < 3 mm) and the need for auxiliary procedures.

RESULTS

Both groups were statistically analyzed for age, sex, BMI, stone size, Hounsfield units (HU), infundibular dimensions, access sheath use, complications (fever, sepsis, hematuria) and hospital stay. No significant differences were found between the two groups in these variables. However, operative time was significantly longer in Group A than in Group B (P value = 0.018). The need for auxiliary procedures was significantly lower in Group A than in Group B (P value = 0.001), and the success rate was significantly higher in Group A than in Group B (P value = 0.001).

CONCLUSION

The T-tilt position and hydrodilatation significantly optimize outcomes and enhance stone-free rates for large lower calyceal stones (10-20 mm). This position improves intraoperative vision and facilitates access to the lower calyx, facilitating the clearance of stone fragments.

摘要

背景

处理下盏结石面临重大挑战。软性输尿管镜检查和激光碎石术(FURSL)是治疗大结石(10 - 20毫米)的标准技术。

目的

本研究评估T形倾斜体位(头低脚高45度并向结石侧侧倾45度)以及根据需要用50毫升生理盐水对下盏进行水扩张在优化下盏结石FURSL治疗的无石率和安全性方面的作用。

方法

经伦理批准后,对197例患者进行了一项前瞻性随机研究。排除13例患者(9例有肾脏异常或既往手术影响解剖结构,4例拒绝参与)。其余184例患者随机分为A组(92例采用T形倾斜体位并进行水扩张)和B组(92例采用截石位并进行水扩张)。通过存储在密封信封中的计算机生成数字进行随机分组。所有患者结石大小为10 - 20毫米,使用7.5FR软性输尿管镜和200微米的Wolf激光光纤进行FURSL治疗。在术后1个月和3个月进行随访CT KUB检查,评估无石状态(无残留结石或残留结石<3毫米)以及辅助手术的必要性。

结果

对两组患者的年龄、性别、BMI、结石大小、亨氏单位(HU)、漏斗部尺寸、是否使用接入鞘、并发症(发热、败血症、血尿)和住院时间进行统计学分析。两组在这些变量上无显著差异。然而,A组的手术时间显著长于B组(P值 = 0.018)。A组辅助手术的必要性显著低于B组(P值 = 0.001),且A组的成功率显著高于B组(P值 = 0.001)。

结论

T形倾斜体位和水扩张显著优化了大下盏结石(10 - 20毫米)的治疗效果并提高了无石率。该体位改善了术中视野并便于进入下盏,有利于结石碎片的清除。

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