Karayiannis Paul, Walls Andrew, Cassidy Roslyn, Beverland David
Orthopaedic Department, Musgrave Park Hospital, Belfast, Northern Ireland, UK.
Arthroplast Today. 2020 Jun 1;6(3):289-295. doi: 10.1016/j.artd.2020.04.005. eCollection 2020 Sep.
Rapidly progressive osteoarthritis (RPO) is a rare condition which is poorly understood. Limited published literature is available. Reported here is a cohort of patients with RPO and acetabular bone loss who underwent primary THA. Risk factors, degree of acetabular bone loss and outcomes are presented. A typical case of RPO is described and investigations discussed. A retrospective audit was undertaken. 49 patients over an 18-year period were included. RPO patients were significantly older ( < 0.01) and had a lower BMI ( = 0.03). The mean acetabular bone loss in this cohort was 10.0 mm. Pathogenesis and risk factors for developing RPO remain unclear and future research is necessary. Repeat imaging in patients with deteriorating symptoms is important and urgent surgery is required maintain bone stock.
快速进展性骨关节炎（RPO）是一种罕见疾病，人们对其了解甚少。已发表的相关文献有限。本文报告了一组患有RPO和髋臼骨丢失并接受初次全髋关节置换术（THA）的患者。介绍了危险因素、髋臼骨丢失程度及治疗结果。描述了一例典型的RPO病例并讨论了相关检查。进行了一项回顾性审计。纳入了18年间的49例患者。RPO患者年龄显著更大（P<0.01）且体重指数更低（P = 0.03）。该队列中髋臼骨丢失的平均程度为10.0毫米。RPO的发病机制和危险因素仍不清楚，未来有必要开展研究。对症状恶化的患者进行重复影像学检查很重要，并且需要紧急手术以维持骨量。
