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快速进展性骨关节炎全髋关节置换术的结局:系统评价。

The outcomes of total hip arthroplasty in rapidly progressive osteoarthritis: a systematic review.

机构信息

Postgraduate Medical Education Centre, West Middlesex University Hospital, Twickenham Road, Isleworth, TW7 6AF, Middlesex, UK.

The Academic Surgical Unit, South West London Elective Orthopaedic Centre, Epsom General Hospital, Dorking Road, Epsom, KT18 7EG, UK.

出版信息

Eur J Orthop Surg Traumatol. 2023 Jul;33(5):1505-1514. doi: 10.1007/s00590-022-03396-8. Epub 2022 Sep 23.

Abstract

PURPOSE

Rapidly progressive osteoarthritis of the hip is an uncommon and poorly understood condition. No universal definition of RPOH exists, however, a loss of joint space of 2 mm or more per year or 50% or more in one year with no other cause can be classed as RPOH. Due to the rapid loss of joint space and associated bone loss, total hip arthroplasty is the only viable treatment option. The aim of this systematic review is to assess the outcomes of THA in RPOH.

METHODS

A systematic search of Embase, Medline and CINAHL databases was performed for studies reporting on the outcomes of patients with RPOH as their primary diagnosis for undergoing THA. Patient demographics, surgical techniques, implant selection, blood loss, morbidity and mortality, length of stay and patient-reported outcomes were amongst the data collected.

RESULTS

Eight studies were found to be eligible, reporting on the outcomes of 270 patients with a mean age of 71. The majority of patients (88.1%) were female and the mean Body Mass Index was 27.6 kg/m. Six of the eight studies reported on the need for additional reconstructive devices and procedures including the use of acetabular roof augmentation, acetabular reinforcement devices and revision acetabular components. Two studies reported increased blood loss in RPOH patients compared with non-RPOH patients (945 ml vs. 578 ml and 473.9 g vs. 353.9 g, respectively).

CONCLUSION

RPOH leads to significant pre-operative morbidity and THA for RPOH has been shown to result in greater blood loss, prolonged operative time and increased complexity of the procedure all of which result in increased cost. There is a paucity of data on the long-term outcomes for these patients and more well-constructed studies are therefore required.

摘要

目的

髋关节进行性骨关节炎是一种不常见且尚未被充分认识的疾病。目前尚不存在 RPOH 的通用定义,然而,每年关节间隙丢失 2 毫米或更多,或一年内丢失 50%或更多,且没有其他原因,则可归类为 RPOH。由于关节间隙迅速丢失以及相关的骨丢失,全髋关节置换术是唯一可行的治疗选择。本系统评价旨在评估 RPOH 患者行全髋关节置换术的治疗效果。

方法

对 Embase、Medline 和 CINAHL 数据库进行系统检索,以查找报告 RPOH 患者作为初次诊断接受全髋关节置换术治疗的患者的研究。收集的数据包括患者人口统计学资料、手术技术、植入物选择、失血量、发病率和死亡率、住院时间和患者报告的结果。

结果

共发现 8 项符合条件的研究,报告了 270 例患者的治疗效果,患者平均年龄为 71 岁。大多数患者(88.1%)为女性,平均体重指数为 27.6kg/m²。8 项研究中有 6 项报告了需要额外的重建装置和手术,包括使用髋臼顶加强、髋臼加强装置和翻修髋臼组件。有 2 项研究报告 RPOH 患者的失血量多于非 RPOH 患者(分别为 945ml 比 578ml 和 473.9g 比 353.9g)。

结论

RPOH 导致术前发病率高,且 RPOH 患者行全髋关节置换术会导致更多失血、手术时间延长和手术复杂性增加,所有这些都会增加成本。目前针对这些患者的长期治疗效果数据较少,因此需要进行更多精心设计的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9827/9510317/4e7383bc3a19/590_2022_3396_Fig1_HTML.jpg

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