Buntin J D, Figge G R
Department of Biological Sciences, University of Wisconsin-Milwaukee 53201.
Pharmacol Biochem Behav. 1988 Nov;31(3):533-40. doi: 10.1016/0091-3057(88)90227-4.
Ingestive behavior and body weight were measured in male and female ring doves given twice daily subcutaneous injections of ovine prolactin (7 mg/kg/day) or vehicle and in male doves given daily intracerebroventricular (ICV) injections of ovine prolactin at doses ranging from 0.1 to 2.0 micrograms/day. Changes induced by ICV administration of turkey prolactin, turkey growth hormone, ovine growth hormone, human growth hormone, and vehicle were also examined. Subcutaneous injections of ovine prolactin markedly increased food intake and body weight in both sexes. Similar effects occurred in dose-related fashion in male doves given ICV injections of ovine prolactin. The three growth hormone preparations also increased feeding and body weight significantly, but turkey prolactin was ineffective in this regard. Changes in drinking generally paralleled feeding patterns but were less pronounced and may have been secondary to feeding changes. We conclude that feeding in this species is strongly stimulated by some prolactin and growth hormone preparations. However, the physiological mechanisms underlying these effects remain to be clarified.
对雄性和雌性环颈鸽每日皮下注射两次绵羊催乳素（7毫克/千克/天）或赋形剂，并对雄性鸽每日脑室内（ICV）注射剂量范围为0.1至2.0微克/天的绵羊催乳素，测量其摄食行为和体重。还研究了ICV注射火鸡催乳素、火鸡生长激素、绵羊生长激素、人生长激素和赋形剂所引起的变化。皮下注射绵羊催乳素显著增加了两性的食物摄入量和体重。ICV注射绵羊催乳素的雄性鸽也出现了类似的剂量相关效应。三种生长激素制剂也显著增加了摄食和体重，但火鸡催乳素在这方面无效。饮水变化通常与摄食模式平行，但不太明显，可能是摄食变化的继发结果。我们得出结论，某些催乳素和生长激素制剂强烈刺激该物种的摄食。然而，这些效应背后的生理机制仍有待阐明。
