1World Health Organization Collaborating Centre on Investment for Health and Well-being, Policy and International Health, Public Health Wales, Wrexham, UK
School of Human Sciences, Bangor University, Wrexham, UK.
BMJ Open. 2020 Jun 7;10(6):e036374. doi: 10.1136/bmjopen-2019-036374.
To estimate the health and financial burden of adverse childhood experiences (ACEs) in England and Wales.
The study combined data from five randomly stratified cross-sectional ACE studies. Population attributable fractions (PAFs) were calculated for major health risks and causes of ill health and applied to disability adjusted life years (DALYs), with financial costs estimated using a modified human capital method.
Households in England and Wales.
15 285 residents aged 18-69.
The outcome measures were PAFs for single (1 ACE) and multiple (2-3 and ≥4 ACEs) ACE exposure categories for four health risks (smoking, alcohol use, drug use, high body mass index) and nine causes of ill health (cancer, type 2 diabetes, heart disease, respiratory disease, stroke, violence, anxiety, depression, other mental illness); and annual estimated DALYs and financial costs attributable to ACEs.
Cumulative relationships were found between ACEs and risks of all outcomes. For health risks, PAFs for ACEs were highest for drug use (Wales 58.8%, England 52.6%), although ACE-attributable smoking had the highest estimated costs (England and Wales, £7.8 billion). For causes of ill health, PAFs for ACEs were highest for violence (Wales 48.9%, England 43.4%) and mental illness (ranging from 29.1% for anxiety in England to 49.7% for other mental illness in Wales). The greatest ACE-attributable costs were for mental illness (anxiety, depression and other mental illness; England and Wales, £11.2 billion) and cancer (£7.9 billion). Across all outcomes, the total annual ACE-attributable cost was estimated at £42.8 billion. The majority of costs related to exposures to multiple rather than a single ACE (ranging from 71.9% for high body mass index to 98.3% for cancer).
ACEs impose a substantial societal burden in England and Wales. Policies and practices that prevent ACEs, build resilience and develop trauma-informed services are needed to reduce burden of disease and avoidable service use and financial costs across health and other sectors.
估计英格兰和威尔士不良儿童经历(ACEs)的健康和经济负担。
该研究结合了五项随机分层 ACE 研究的数据。计算了主要健康风险和健康不良原因的人群归因分数(PAFs),并将其应用于残疾调整生命年(DALYs),使用改良的人力资本法估算财务成本。
英格兰和威尔士的家庭。
15285 名 18-69 岁的居民。
结果衡量标准是单一(1 ACE)和多种(2-3 和≥4 ACE)ACE 暴露类别对四个健康风险(吸烟、饮酒、吸毒、高体重指数)和九个健康不良原因(癌症、2 型糖尿病、心脏病、呼吸疾病、中风、暴力、焦虑、抑郁、其他精神疾病)的 PAFs;以及归因于 ACE 的年度估计 DALYs 和财务成本。
发现 ACE 与所有结果的风险之间存在累积关系。对于健康风险,ACE 归因于吸烟的 PAF 最高(威尔士 58.8%,英格兰 52.6%),尽管 ACE 归因于吸烟的估计成本最高(英格兰和威尔士为 78 亿英镑)。对于健康不良的原因,ACE 归因于暴力的 PAF 最高(威尔士 48.9%,英格兰 43.4%)和精神疾病(从英格兰的焦虑症 29.1%到威尔士的其他精神疾病 49.7%不等)。ACE 归因于精神疾病(焦虑症、抑郁症和其他精神疾病;英格兰和威尔士为 112 亿英镑)和癌症(79 亿英镑)的成本最高。在所有结果中,估计 ACE 归因于每年的总成本为 428 亿英镑。大部分成本与多次暴露而非单一 ACE 相关(从高体重指数的 71.9%到癌症的 98.3%不等)。
ACE 在英格兰和威尔士造成了巨大的社会负担。需要预防 ACE、建立韧性和发展创伤知情服务的政策和做法,以减少疾病负担以及避免整个卫生和其他部门的不必要服务使用和财务成本。