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微创外科手术在脊柱转移性肿瘤治疗中的作用

The Role of Minimal Access Surgery in the Treatment of Spinal Metastatic Tumors.

作者信息

Barzilai Ori, Bilsky Mark H, Laufer Ilya

机构信息

Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Weill Cornell Medical College, New York, NY, USA.

出版信息

Global Spine J. 2020 Apr;10(2 Suppl):79S-87S. doi: 10.1177/2192568219895265. Epub 2020 May 28.

Abstract

STUDY DESIGN

Literature review.

OBJECTIVE

To provide an overview of the recent advances in minimal access surgery (MAS) for spinal metastases.

METHODS

Literature review.

RESULTS

Experience gained from MAS in the trauma, degenerative and deformity settings has paved the road for MAS techniques for spinal cancer. Current MAS techniques for the treatment of spinal metastases include percutaneous instrumentation, mini-open approaches for decompression and tumor resection with or without tubular/expandable retractors and thoracoscopy/endoscopy. Cancer care requires a multidisciplinary effort and adherence to treatment algorithms facilitates decision making, ultimately improving patient outcomes. Specific algorithms exist to help guide decisions for MAS for extradural spinal metastases. One major paradigm shift has been the implementation of percutaneous stabilization for treatment of neoplastic spinal instability. Percutaneous stabilization can be enhanced with cement augmentation for increased durability and pain palliation. Unlike osteoporotic fractures, kyphoplasty and vertebroplasty are known to be effective therapies for symptomatic pathologic compression fractures as supported by high level evidence. The integration of systemic body radiation therapy for spinal metastases has eliminated the need for aggressive tumor resection allowing implementation of MAS epidural tumor decompression via tubular or expandable retractors and preliminary data exist regarding laser interstitial thermal therapy and radiofrequency ablation for tumor control. Neuronavigation and robotic systems offer increased precision, facilitating the role of MAS for spinal metastases.

CONCLUSIONS

MAS has a significant role in the treatment of spinal metastases. This review highlights the current utilization of minimally invasive surgical strategies for treatment of spinal metastases.

摘要

研究设计

文献综述。

目的

概述脊柱转移瘤微创外科手术(MAS)的近期进展。

方法

文献综述。

结果

在创伤、退行性疾病及畸形手术中积累的MAS经验为脊柱肿瘤的MAS技术奠定了基础。目前用于治疗脊柱转移瘤的MAS技术包括经皮器械置入、使用或不使用管状/可扩张牵开器的小切口减压及肿瘤切除术以及胸腔镜/内镜检查。癌症治疗需要多学科协作,遵循治疗方案有助于决策制定,最终改善患者预后。存在特定的方案来指导硬膜外脊柱转移瘤MAS治疗的决策。一个主要的模式转变是采用经皮固定治疗肿瘤性脊柱不稳。可通过骨水泥强化增强经皮固定,以提高耐用性并缓解疼痛。与骨质疏松性骨折不同,有高级别证据支持椎体后凸成形术和椎体成形术是治疗有症状病理性压缩骨折的有效疗法。脊柱转移瘤全身放射治疗的整合消除了积极肿瘤切除的必要性,使得能够通过管状或可扩张牵开器实施MAS硬膜外肿瘤减压,并且存在关于激光间质热疗和射频消融用于肿瘤控制的初步数据。神经导航和机器人系统提高了手术精度,促进了MAS在脊柱转移瘤治疗中的作用。

结论

MAS在脊柱转移瘤治疗中具有重要作用。本综述强调了目前微创外科手术策略在脊柱转移瘤治疗中的应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14db/7263343/15bb5de532db/10.1177_2192568219895265-fig1.jpg

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