Department of Dermatology, School of Medicine, Inha University, Incheon, Republic of Korea.
J Cutan Pathol. 2020 Nov;47(11):1039-1041. doi: 10.1111/cup.13776. Epub 2020 Jul 16.
Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory dermatosis of the anogenital area, and approximately 15% to 20% of patients with LSA have extragenital lesions. Here, we report the case of an 18-year-old Korean man presenting with multiple asymptomatic punctated hypopigmented atrophic macules on the dorsa of both feet. Dermoscopic examination revealed hypopigmented atrophic macules with several central keratotic plugs. The histopathologic findings indicated LSA but were confined to the acrosyringium. Based on the clinical and histopathological findings, the patient was diagnosed with an acrosyringeal variant of extragenital LSA. The patient in this case showed a unique histopathological finding in which the typical features of LSA were confined to the acrosyringium, as well as an unusual clinical presentation of non-coalescing atrophic punctate macules on the dorsum of the feet.
硬化性萎缩性苔藓(lichen sclerosus et atrophicus,LSA)是一种发生于肛门生殖器区域的慢性炎症性皮肤病,约 15%至 20%的 LSA 患者存在外阴病变。在此,我们报告了 1 例 18 岁韩国男性患者,其双足足背出现多个无症状的点状色素减退性萎缩性斑片。皮肤镜检查显示色素减退性萎缩性斑片,伴数个中央角化栓。组织病理学检查提示 LSA,但局限于外毛根鞘。根据临床和组织病理学检查,患者被诊断为外阴 LSA 的外毛根鞘变异型。本例患者表现出一种独特的组织病理学发现,即 LSA 的典型特征局限于外毛根鞘,以及足部背侧非融合性点状萎缩性斑片的不常见临床表现。