Davide Prestia, Andrea Pozza, Martina Olcese, Andrea Escelsior, Davide Dettore, Mario Amore
Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Infant-Maternal Science, Section of Psychiatry, University of Genoa, Italy; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.
Psychiatry Res. 2020 Sep;291:113213. doi: 10.1016/j.psychres.2020.113213. Epub 2020 Jun 9.
The containment measures implemented to reduce the progression of the COVID-19 pandemic can increase the risk of serious mental disorders, including obsessive-compulsive disorder (OCD). The general fear of getting infected and the importance given to personal hygiene, may have a negative impact on this clinical population. In a group of patients with OCD who had completed an evidence-based therapeutic path for OCD before the quarantine, this study evaluated the changes on OCD symptoms during the quarantine and investigated the effects of contamination symptoms and remission state before the quarantine on OCD symptom worsening during the quarantine. The Yale-Brown Obsessive Compulsive (Y-BOCS) Severity score, administered before the quarantine, was re-administered after six weeks since the beginning of the complete lockdown. A significant increase in obsession and compulsion severity emerged. Remission status on OCD symptoms and having contamination symptoms before the quarantine were significantly associated with more elevated OCD symptom worsening during the quarantine. To our knowledge, this is the first study which assessed OCD symptoms at the COVID-19 time. Our results support the need to improve relapse prevention during the period of social restrictions and develop alternative strategies such as online consultations and digital psychiatric management.
为减缓新冠疫情蔓延而实施的防控措施可能会增加包括强迫症（OCD）在内的严重精神障碍风险。对感染的普遍恐惧以及对个人卫生的重视，可能会对这类临床人群产生负面影响。在一组在隔离前已完成基于证据的强迫症治疗疗程的患者中，本研究评估了隔离期间强迫症症状的变化，并调查了隔离前的污染症状和缓解状态对隔离期间强迫症症状恶化的影响。在完全封锁开始六周后，重新进行了在隔离前进行的耶鲁布朗强迫症（Y-BOCS）严重程度评分。强迫观念和强迫行为的严重程度显著增加。隔离前强迫症症状的缓解状态和有污染症状与隔离期间强迫症症状更严重的恶化显著相关。据我们所知，这是第一项在新冠疫情期间评估强迫症症状的研究。我们的结果支持在社会限制期间加强预防复发的必要性，并制定替代策略，如在线咨询和数字精神科管理。
