Zhang M H, Ren B, Zhao S Z, Wang B L
Department of Emergency, the Second Affiliated Hospital of Air Force Military Medical University, Xi'an 710038, China.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2020 May 20;38(5):378-380. doi: 10.3760/cma.j.cn121094-20191103-00514.
To investigate the diagnosis and treatment of occupational acute methanol poisoning. Retrospective analysis of the clinical data of 5 cases of occupational acute me thanol poisoning admitted from October 11 to 12, 2018. The first patient was diagnosed with severe acute methanol poisoning and died after treatment with mechanical ventilation, hemodialysis, and detoxification by ethanol and folic acid for 38 hours. The remaining four cases were all diagnosed with mild acute methanol poisoning and were discharged from hospital after active symptomatic support treatment for 63 to 69 hours. Fuhermore, all the four patients were followed up for one year and without sequelaes. Early evaluation of the disease, early combination with hemodialysis, and use of detoxification drugs are the key to rescue occupational acute methanol poisoning.
探讨职业性急性甲醇中毒的诊断与治疗。回顾性分析2018年10月11日至12日收治的5例职业性急性甲醇中毒患者的临床资料。首例患者被诊断为重度急性甲醇中毒，经机械通气、血液透析以及乙醇和叶酸解毒治疗38小时后死亡。其余4例均被诊断为轻度急性甲醇中毒，经积极对症支持治疗63至69小时后出院。此外，对这4例患者均进行了为期一年的随访，未出现后遗症。早期评估病情、早期联合血液透析以及使用解毒药物是抢救职业性急性甲醇中毒的关键。
