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大鼠唾液腺长期导管结扎对类胰蛋白酶活性的影响。

Effects of prolonged duct ligation of the rat salivary glands on the activity of trypsin-like protease.

作者信息

Ikeno K, Saikatsu S, Uno T, Ikeno T

机构信息

Department of Oral Biochemistry, Tohoku Dental University, Koriyama, Japan.

出版信息

Arch Oral Biol. 1988;33(8):613-5. doi: 10.1016/0003-9969(88)90137-9.

DOI:10.1016/0003-9969(88)90137-9
PMID:3254130
Abstract

The effects of ligation on body weight, protease activity and hair kynurenine content were observed. The body weights of parotid gland(PT)-ligated and of combined submandibular (SM)-, sublingual (SL)- and PT-ligated rats were much less than those of sham-operated controls. However, the weights of SM,SL-ligated rats were similar to those of controls. The activity of trypsin-like protease in the duct-ligated submandibular gland was significantly reduced to 0.3-0.7 per cent of that in controls. Protein concentration also decreased in the duct-ligated submandibular gland. Kynurenine content in the hair of duct-ligated rats was higher than that in controls.

摘要

观察了结扎对体重、蛋白酶活性和毛发犬尿氨酸含量的影响。腮腺(PT)结扎以及颌下腺(SM)、舌下腺(SL)和PT联合结扎大鼠的体重明显低于假手术对照组。然而,SM、SL结扎大鼠的体重与对照组相似。导管结扎的颌下腺中类胰蛋白酶的活性显著降低至对照组的0.3%-0.7%。导管结扎的颌下腺中的蛋白质浓度也降低。导管结扎大鼠毛发中的犬尿氨酸含量高于对照组。

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