Chen Guocai, Ye Xiangling, Guan Yingxin, Liu Wengang, Du Jianping, Yao Nan, Xu Xuemeng
The Fifth Clinical Medical School, Guangzhou University of Chinese Medicine.
Guangdong Second Traditional Chinese Medicine Hospital.
Medicine (Baltimore). 2020 Jun 12;99(24):e20659. doi: 10.1097/MD.0000000000020659.
Knee osteoarthritis (KOA) is a common progressive joint disorder in old people. Bushen huoxue (BSHX) is a classical method of TCM in treating KOA. However, there is no systematic review related to BSHX for KOA. The purpose of this study is to provide a comprehensive and reliable evaluation of the clinical evidence of BSHX in the treatment of KOA.
We searched relevant studies on BSHX for KOA from the databases of PubMed, Embase, MEDLINE, Cochrane Library Central Register of Controlled Trials, China national knowledge infrastructure database (CNKI), Wan fang database, Chongqing VIP information, and SinoMed from their inception to May 2020. Two researchers will select and evaluate qualified studies independently. The primary outcomes of this review will focus on pain intensity. The meta-analyses will be performed by using the RevMan 5.3.
The study will provide a comprehensive evaluation of the efficacy and safety of the BSHX method for patients with KOA.
The results of this systematic review will provide evidence to judge whether BSHX is an effective intervention for patients with KOA.
膝关节骨关节炎（KOA）是老年人常见的进行性关节疾病。补肾活血（BSHX）是中医治疗KOA的经典方法。然而，尚无关于BSHX治疗KOA的系统评价。本研究的目的是对BSHX治疗KOA的临床证据提供全面可靠的评估。
我们从PubMed、Embase、MEDLINE、Cochrane图书馆对照试验中央注册库、中国国家知识基础设施数据库（CNKI）、万方数据库、重庆维普资讯和中国生物医学文献数据库中检索从建库至2020年5月有关BSHX治疗KOA的相关研究。两名研究人员将独立选择并评估合格的研究。本评价的主要结局将聚焦于疼痛强度。将使用RevMan 5.3进行荟萃分析。
本研究将对BSHX方法治疗KOA患者的疗效和安全性提供全面评估。
本系统评价的结果将为判断BSHX是否为KOA患者的有效干预措施提供证据。
