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补肾活血法对卵巢储备功能下降女性的影响:一项系统评价与Meta分析方案

Effects of Bushen Huoxue method for female with decreased ovarian reserve: A protocol for systematic review and meta-analysis.

作者信息

Xie Zhuoting, Li Yin, Chen Zehua, Cao Qiuyu, Zhang Chunren, Fei Yang, Li Kunyin, Guan Yongge

机构信息

The Third Clinical Medical School.

The First Clinical Medical School, Guangzhou University of Chinese Medicine.

出版信息

Medicine (Baltimore). 2020 Oct 23;99(43):e22957. doi: 10.1097/MD.0000000000022957.

DOI:10.1097/MD.0000000000022957
PMID:33120859
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7581047/
Abstract

BACKGROUND

Decreased ovarian reserve (DOR) is a common reproductive barrier in female. Bushen Huoxue (BSHX) method of TCM is widely applied to treat DOR clinically. The purpose of this study is to provide a systemic and comprehensive evaluation of BSHX in the treatment of DOR.

METHODS

We have registered this protocol with OSF registry and the DOI is 10.17605/OSF.IO/QNUE2. We will search 4 English databases (PubMed, EMBASE, MEDLINE, Cochrane Library) and four Chinese databases (China national knowledge infrastructure database, Wanfang database, VIP and Superstar database) from their inception to August 10, 2020. Two authors will search and extract independently all related studies. RevMan 5.3 software will be applied to synthesize data.

RESULTS

The results of this study will be published in a scientific journal after peer-review.

CONCLUSION

This systematic review will provide reliable evidences for clinicians, and help them make decisions in DOR management.

摘要

背景

卵巢储备功能下降(DOR)是女性常见的生殖障碍。中医补肾活血法在临床上广泛应用于治疗DOR。本研究旨在对补肾活血法治疗DOR进行系统全面的评价。

方法

我们已在开放科学框架(OSF)注册库中注册了本方案,数字对象标识符(DOI)为10.17605/OSF.IO/QNUE2。我们将检索4个英文数据库(PubMed、EMBASE、MEDLINE、Cochrane图书馆)和4个中文数据库(中国知网数据库、万方数据库、维普数据库和超星发现数据库),检索时间范围从建库至2020年8月10日。两名作者将独立检索并提取所有相关研究。将应用RevMan 5.3软件进行数据合成。

结果

本研究结果将在同行评审后发表于科学期刊。

结论

本系统评价将为临床医生提供可靠证据,帮助他们在DOR管理中做出决策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ea4/7581047/1727c94fd8c0/medi-99-e22957-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ea4/7581047/1727c94fd8c0/medi-99-e22957-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ea4/7581047/1727c94fd8c0/medi-99-e22957-g001.jpg

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本文引用的文献

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Medicine (Baltimore). 2020 Jun 12;99(24):e20659. doi: 10.1097/MD.0000000000020659.
2
Do young women with unexplained infertility show manifestations of decreased ovarian reserve?不明原因不孕的年轻女性是否表现出卵巢储备功能下降的迹象?
J Assist Reprod Genet. 2019 Jun;36(6):1143-1152. doi: 10.1007/s10815-019-01467-0. Epub 2019 May 21.
3
Diminished ovarian reserve versus ovarian aging: overlaps and differences.
卵巢储备功能减退与卵巢衰老:重叠与差异。
Curr Opin Obstet Gynecol. 2019 Jun;31(3):139-147. doi: 10.1097/GCO.0000000000000536.
4
[Effects of ginger-separated moxibustion at points combined with formula on patients with decreased ovarian reserve function].[隔姜灸穴位联合方剂对卵巢储备功能下降患者的影响]
Zhongguo Zhen Jiu. 2017 Oct 12;37(10):1057-60. doi: 10.13703/j.0255-2930.2017.10.008.
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Premature ovarian failure.卵巢早衰
Prz Menopauzalny. 2017 Jun;16(2):51-56. doi: 10.5114/pm.2017.68592. Epub 2017 Jun 30.
6
Immunomodulatory mechanism of Bushen Huoxue Recipe alleviates cyclophosphamide-induced diminished ovarian reserve in mouse model.补肾活血方的免疫调节机制减轻环磷酰胺诱导的小鼠模型卵巢储备功能下降
J Ethnopharmacol. 2017 Aug 17;208:44-56. doi: 10.1016/j.jep.2017.06.022. Epub 2017 Jun 21.
7
Decreased Ovarian Reserve Predicts Inexplicability of Recurrent Miscarriage? A Retrospective Analysis.卵巢储备功能下降预示复发性流产的不可解释性?一项回顾性分析。
PLoS One. 2016 Sep 14;11(9):e0161606. doi: 10.1371/journal.pone.0161606. eCollection 2016.
8
ESHRE Guideline: management of women with premature ovarian insufficiency.ESHRE 指南:卵巢早衰妇女的管理。
Hum Reprod. 2016 May;31(5):926-37. doi: 10.1093/humrep/dew027. Epub 2016 Mar 22.
9
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Gynecol Endocrinol. 2016 Jul;32(7):534-7. doi: 10.3109/09513590.2015.1137095. Epub 2016 Feb 1.
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