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腹腔镜下 Frey 手术治疗日本慢性胰腺炎患者一例

Laparoscopic Frey's Procedure for Chronic Pancreatitis in a Japanese Patient.

机构信息

Department of Hepato-Biliary-Pancreatic Surgery, Osaka City General Hospital, Osaka City, Osaka, Japan.

Department of Surgery, Meiwa General Hospital, Kobe, Hyogo, Japan.

出版信息

Am J Case Rep. 2020 Jun 15;21:e924206. doi: 10.12659/AJCR.924206.

Abstract

BACKGROUND Chronic pancreatitis is a slowly progressive inflammatory disease, affecting patients' quality of life due to chronic pain as well as endocrine and exocrine pancreatic insufficiency. Patients often choose surgery if medical and endoscopic interventions fail. Surgical approaches for chronic pancreatitis can be categorized as follows: resection of the diseased gland, diversion and drainage of the dilated pancreatic duct, or a combination of these approaches. Frey's procedure, which involves resection and drainage by longitudinal pancreaticojejunostomy and coring out of the pancreatic head, is reserved for patients with debilitating pain. Although laparoscopic surgery is gaining popularity in recent years due to its noninvasiveness and cosmetic benefit, few reports describe performing Frey's procedure laparoscopically. CASE REPORT A 36-year-old Japanese female with chronic pancreatitis complained of back pain and pain in the left upper quadrant abdomen. Plain computed tomography of her abdomen revealed a dilated main pancreatic duct containing diffuse calculi extending to the pancreatic parenchyma. Laboratory findings, including amylase level, were within normal ranges. She was diagnosed with chronic pancreatitis, and subsequently underwent a laparoscopic Frey's procedure. To our knowledge, we are the first to improve operative field visibility by using a Penrose drain to move the stomach from the line of sight. Postoperatively, the patient did well and was discharged 10 days after surgery. She remained symptom-free without medications for 80 months. CONCLUSIONS Due to its noninvasive nature and cosmetic advantages, laparoscopic Frey's procedure may be an attractive therapeutic option for chronic pancreatitis.

摘要

背景

慢性胰腺炎是一种缓慢进展的炎症性疾病,由于慢性疼痛以及内、外分泌胰腺功能不全,会影响患者的生活质量。如果内科和内镜介入治疗失败,患者通常会选择手术。慢性胰腺炎的手术方法可分为以下几类:病变腺体切除术、扩张胰管的引流和分流术,或这些方法的联合应用。Frey 手术(通过纵向胰肠吻合术和胰头钻孔进行切除和引流)适用于患有致残性疼痛的患者。尽管近年来由于其非侵入性和美容优势,腹腔镜手术越来越受欢迎,但很少有报道描述腹腔镜下进行 Frey 手术。

病例报告

一位 36 岁的日本女性患有慢性胰腺炎,主诉背部疼痛和左上腹部疼痛。腹部平扫 CT 显示扩张的主胰管内弥漫性结石延伸至胰腺实质。实验室检查结果(包括淀粉酶水平)均在正常范围内。她被诊断为慢性胰腺炎,随后接受了腹腔镜 Frey 手术。据我们所知,我们首次使用 Penrose 引流管将胃从视线中移开,从而改善了手术视野的可见度。术后,患者恢复良好,术后 10 天出院。她在 80 个月内没有出现任何症状,也无需服药。

结论

由于其非侵入性和美容优势,腹腔镜 Frey 手术可能是慢性胰腺炎的一种有吸引力的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/652e/7319076/b623766bed80/amjcaserep-21-e924206-g001.jpg

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