Kilburn Daniel J, Chiow Adrian K H, Leung Universe, Siriwardhane Mehan, Cavallucci David J, Bryant Richard, O'Rourke Nicholas A
Hepatopancreatobiliary Unit, Department of Surgery, Royal Brisbane Hospital, Brisbane, Queensland, 4029, Australia.
School of Medicine, The University of Queensland, Brisbane, Australia.
J Gastrointest Surg. 2017 May;21(5):904-909. doi: 10.1007/s11605-016-3343-4. Epub 2016 Dec 26.
The Frey procedure has been demonstrated to be an effective surgical technique to treat patients with painful large duct chronic pancreatitis. More commonly reported as an open procedure, we report our experience with a minimally invasive approach to the Frey procedure. Four consecutive patients underwent a laparoscopic Frey procedure at our institution from January 2012 to July 2015. We herein report our technique and describe short- and medium-term outcomes. The median age was 40 years old. The median duration of pancreatic pain prior to surgery was 12 years. Median operative time and intraoperative blood loss was 130 min (100-160 min) and 60 mL (50-100 mL), respectively. The median length of stay was 7 days (3-40 days) and median follow-up was 26 months (12-30 months). There was one major postoperative complication requiring reoperation. Within 6 months, in all four patients, frequency of pain and analgesic requirement reduced significantly. Two patients appeared to have resolution of pancreatic exocrine insufficiency. The Frey procedure is possible laparoscopically with acceptable short- and medium-term outcomes in well-selected patients.
弗雷氏手术已被证明是治疗疼痛性大导管慢性胰腺炎患者的一种有效手术技术。该手术更常被报道为开放性手术，我们报告了我们采用微创方法进行弗雷氏手术的经验。2012年1月至2015年7月，我们机构有4例连续患者接受了腹腔镜弗雷氏手术。我们在此报告我们的技术并描述短期和中期结果。患者中位年龄为40岁。术前胰腺疼痛的中位持续时间为12年。中位手术时间和术中失血量分别为130分钟（100 - 160分钟）和60毫升（50 - 100毫升）。中位住院时间为7天（3 - 40天），中位随访时间为26个月（12 - 30个月）。有1例严重术后并发症需要再次手术。在6个月内，所有4例患者的疼痛频率和镇痛需求均显著降低。2例患者的胰腺外分泌功能不全似乎得到缓解。对于精心挑选的患者，腹腔镜下进行弗雷氏手术是可行的，且具有可接受的短期和中期结果。
