Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Nat Rev Immunol. 2020 Aug;20(8):453-454. doi: 10.1038/s41577-020-0367-5.
A new multisystem inflammatory syndrome apparently related to infection with SARS-CoV-2 has recently been reported in older children (known as MIS-C), manifested by severe abdominal pain, cardiac dysfunction and shock. Here, I discuss the similarities and differences between MIS-C and Kawasaki disease, focusing on their epidemiology, aetiology and pathophysiological mechanisms.
一种新的多系统炎症综合征(MIS-C)显然与 SARS-CoV-2 感染有关,最近在较大儿童中报告(称为 MIS-C),表现为严重腹痛、心功能障碍和休克。在这里,我讨论了 MIS-C 和川崎病之间的异同,重点是它们的流行病学、病因和病理生理机制。