Noorani Tehseen, Alderson-Day Ben
Department of Anthropology, Durham University, South Road, Durham DH1 3LE, UK.
Department of Psychology, Durham University, South Road, Durham, DH1 3LE, UK.
Neurosci Conscious. 2020 Jun 12;2020(1):niaa007. doi: 10.1093/nc/niaa007. eCollection 2020.
In 'REBUS and the Anarchic Brain: Towards a Unified Model of the Brain Action of Psychedelics', Carhart-Harris and Friston offer an important analysis of what the predictive processing framework has to offer our understanding of psychedelic experiences, providing an invaluable ground for psychedelic psychiatry. While applauding this, we encourage paying greater attention to contextual factors shaping extreme experiences and their sequalae, and suggest that the authors' comparisons with certain non-psychedelic altered states may overlook more informative parallels that can be drawn elsewhere. Addressing both points will prove fruitful, ultimately, in identifying the mechanisms of action of greatest interest in psychedelic experiences.
在《字谜游戏与无政府大脑：迈向迷幻药大脑作用的统一模型》一文中，卡哈特 - 哈里斯和弗里斯顿对预测处理框架能为我们理解迷幻体验提供什么进行了重要分析，为迷幻精神病学提供了宝贵的基础。在对此表示赞赏的同时，我们鼓励更多地关注塑造极端体验及其后果的背景因素，并指出作者将其与某些非迷幻改变状态的比较可能忽略了在其他地方可以找到的更具启发性的相似之处。最终，解决这两个问题将有助于确定迷幻体验中最值得关注的作用机制。
