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阿拉伯虎眼万年青中毒是犬类视力损害和不可逆失明的一个潜在原因。

Intoxication with Ornithogalum arabicum is a potential cause of visual impairment and irreversible blindness in dogs.

作者信息

Slenter Inge J M, Djajadiningrat-Laanen Sylvia C, de Vries Irma, Dijkman Marieke A

机构信息

Ophthalmology Section, Department of Clinical Sciences of Companion Animals, Utrecht University, the Netherlands.

Dutch Poisons Information Centre (DPIC), University Medical Centre Utrecht, Utrecht University, the Netherlands.

出版信息

Toxicon X. 2019 Sep 18;4:100014. doi: 10.1016/j.toxcx.2019.100014. eCollection 2019 Oct.

DOI:10.1016/j.toxcx.2019.100014
PMID:32550571
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7286106/
Abstract

We describe two dogs with persistent visual impairment after initially mild intoxication signs following ingestion of plant material. Additionally, a 12-year analysis of the Dutch Poisons Information Centre database additionally reveals that ingestion of plant material can be potentially life-threatening to companion animals. Further studies are necessary to confirm the involvement of cardiac glycoside-like toxins present in and the toxicity of these substances to the retina.

摘要

我们描述了两只狗，它们在摄入植物材料后最初出现轻度中毒症状，但随后出现了持续性视力障碍。此外，对荷兰毒物信息中心数据库进行的一项为期12年的分析还显示，摄入植物材料可能会对伴侣动物构成潜在的生命威胁。有必要进行进一步研究，以确认植物材料中存在的类强心苷毒素的作用以及这些物质对视网膜的毒性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f949/7286106/d5e830501b08/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f949/7286106/4df89851fa9c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f949/7286106/d5e830501b08/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f949/7286106/4df89851fa9c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f949/7286106/d5e830501b08/gr2.jpg

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Digoxin Inhibits Induction of Experimental Autoimmune Uveitis in Mice, but Causes Severe Retinal Degeneration.地高辛可抑制小鼠实验性自身免疫性葡萄膜炎的诱导，但会导致严重的视网膜变性。
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