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锡兰金环蛇咬伤导致的急性神经肌肉麻痹、横纹肌溶解和长期神经功能缺损:来自斯里兰卡一家蛇类饲养园的两例真实病例

Acute neuromuscular paralysis, rhabdomyolysis and long lasting neurological deficits in Ceylon krait () bites: Two authentic cases from a serpentarium in Sri Lanka.

作者信息

Kularatne S A M, Colombage Anuradha, de Silva Anslem, Weerasinghe Vajira, Rathnayaka R M M K Namal

机构信息

Department of Medicine, Faculty of Medicine, University of Peradeniya, Sri Lanka.

Teaching Hospital Peradeniya, Sri Lanka.

出版信息

Toxicon X. 2019 Oct 2;4:100015. doi: 10.1016/j.toxcx.2019.100015. eCollection 2019 Oct.

Abstract

The Ceylon krait () is a highly venomous elapid snake endemic to Sri Lanka. Its bites are rare and only seven reports are found in the literature. Therefore, the clinical manifestations and natural history of envenoming of Ceylon krait are not well studied yet. Neuroparalysis is the main clinical manifestation of their bites. We report two cases of proven Ceylon krait bites of two young snake keepers working in a serpentarium. They developed acute neuroparalysis, abdominal pain and a period of amnesia. The first patient developed myalgia and increased level of serum creatine kinase suggestive of rhabdomyolysis. One was treated with Indian polyvalent antivenom and both recovered with some long-lasting clinical disabilities namely impairment of sensation of the bitten arm and persistent refraction errors in the eyes in the first patient. The second patient had persistent marked nystagmus.

摘要

锡兰金环蛇()是一种剧毒眼镜蛇科蛇类,为斯里兰卡特有。其咬伤情况罕见,文献中仅发现七例报告。因此,锡兰金环蛇咬伤的临床表现和自然病史尚未得到充分研究。神经麻痹是其咬伤的主要临床表现。我们报告了两例在蛇类饲养馆工作的年轻养蛇人被锡兰金环蛇咬伤确诊的病例。他们出现了急性神经麻痹、腹痛和一段时间的失忆。首例患者出现肌痛,血清肌酸激酶水平升高,提示横纹肌溶解。其中一例接受了印度多价抗蛇毒血清治疗,两人均康复,但仍有一些长期的临床残疾,首例患者被咬手臂感觉受损,眼睛持续存在屈光不正。第二例患者有持续明显的眼球震颤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c16a/7286062/ecf67d4c0187/gr1.jpg

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