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马来环蛇（Bungarus candidus，林奈）所致严重神经毒性中毒：对抗蛇毒血清和抗胆碱酯酶的反应

Severe neurotoxic envenoming by the Malayan krait Bungarus candidus (Linnaeus): response to antivenom and anticholinesterase.

作者信息

Warrell D A, Looareesuwan S, White N J, Theakston R D, Warrell M J, Kosakarn W, Reid H A

出版信息

Br Med J (Clin Res Ed). 1983 Feb 26;286(6366):678-80. doi: 10.1136/bmj.286.6366.678.

DOI:10.1136/bmj.286.6366.678
PMID:6402200
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1547089/
Abstract

Five patients were bitten by the Malayan krait Bungarus candidus (Linnaeus) in eastern Thailand or north western Malaya. Two patients were not envenomed but the other three developed generalised paralysis which progressed to respiratory paralysis in two cases, one of which ended fatally. One patient showed parasympathetic abnormalities. Anticholinesterase produced a dramatic improvement in one patient. Another patient probably benefited from paraspecific antivenom. The efficacy of antivenoms and adjuvants such as anticholinesterases in patients with neurotoxic envenoming requires further study.

摘要

5名患者在泰国东部或马来西亚西北部被马来环蛇（Bungarus candidus，林奈）咬伤。2名患者未出现中毒症状，但其他3名患者出现全身麻痹，其中2例进展为呼吸麻痹，1例死亡。1名患者出现副交感神经异常。抗胆碱酯酶药物使1名患者病情显著改善。另1名患者可能受益于异种特异性抗蛇毒血清。抗蛇毒血清和抗胆碱酯酶等佐剂在神经毒性中毒患者中的疗效需要进一步研究。

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本文引用的文献

1
VENOMOUS SNAKE BITE IN PAPUA AND ITS TREATMENT WITH TRACHEOTOMY, ARTIFICIAL RESPIRATION AND ANTIVENENE.巴布亚的毒蛇咬伤及其气管切开术、人工呼吸和抗蛇毒血清治疗
Trans R Soc Trop Med Hyg. 1964 May;58:263-73. doi: 10.1016/0035-9203(64)90040-9.
2
Diagnosis, prognosis, and treatment of sea-snake bite.
Lancet. 1961 Aug 19;2(7199):399-402. doi: 10.1016/s0140-6736(61)92483-7.
3
Snake bite in India.印度的蛇咬伤情况。
Indian J Med Res. 1954 Oct;42(4):661-86.
4
Neurological aspects of ophitoxemia (Indian krait)- A clinico-electromyographic study.眼镜蛇毒血症（印度金环蛇）的神经学方面——一项临床肌电图研究。
Indian J Med Res. 1981 Feb;73:269-76.
5
Observations on the bite of the Mozambique spitting cobra (Naja mossambica mossambica).关于莫桑比克喷毒眼镜蛇（Naja mossambica mossambica）咬伤的观察报告。
S Afr Med J. 1982 Feb 27;61(9):308-13.
6
Neostigmine in the treatment of Elapidae bites.
J Assoc Physicians India. 1972 Jul;20(7):503-9.
7
External ophthalmoplegia in elapidae bites and its response to neostigmine.
Neurol India. 1975 Jun;23(2):109-10.
8
Acute renal failure with myoglobinuria after tiger snake bite.虎蛇咬伤后伴肌红蛋白尿的急性肾衰竭
Med J Aust. 1975 Oct 18;2(16):638-41.
9
Necrosis, haemorrhage and complement depletion following bites by the spitting cobra (Naja nigricollis).喷毒眼镜蛇（黑颈眼镜蛇）咬伤后的坏死、出血及补体消耗。
Q J Med. 1976 Jan;45(177):1-22.
10
Micro-ELISA for detecting and assaying snake venom and venom-antibody.
Lancet. 1977 Sep 24;2(8039):639-41. doi: 10.1016/s0140-6736(77)92502-8.