Kempf Dale J, Marsh Kennan C
Discovery and Development Sciences, AbbVie, 1 North Waukegan Road, North Chicago, Illinois 60064, United States.
ACS Med Chem Lett. 2020 Mar 27;11(6):1094-1100. doi: 10.1021/acsmedchemlett.0c00051. eCollection 2020 Jun 11.
Tropical diseases that disproportionally affect the world's poorest people have traditionally been neglected from research efforts toward the discovery and development of new and effective therapies. Over the past two decades, major global health funders have made efforts to bring together various research institutions to work together in these disease areas offering little or no commercial return. This work describes the genesis and growth of an informal program devoted to contributing to new therapies for neglected tropical diseases within the environment of a major biopharmaceutical company (AbbVie).
传统上,那些对世界上最贫困人口影响尤为严重的热带疾病,在旨在发现和开发新的有效疗法的研究工作中一直被忽视。在过去二十年里,全球主要的卫生资助机构努力促使各类研究机构在这些几乎没有或完全没有商业回报的疾病领域开展合作。本文介绍了一个非正式项目的起源与发展,该项目致力于在一家大型生物制药公司(艾伯维)的环境中,为被忽视热带疾病的新疗法做出贡献。