Suppr超能文献

肌肉注射阿法沙龙、布托啡诺和咪达唑仑联合使用作为一种新型的保定方案用于3只环尾狐猴()。

Combination of intramuscular alfaxalone, butorphanol, and midazolam as a novel immobilization protocol in 3 ring-tailed lemurs ().

作者信息

Pentsou Kyratsoula, Huuskonen Vilhelmiina

机构信息

UCD Veterinary Hospital, School of Veterinary Medicine, University College Dublin, Belfield, Dublin 4 Ireland.

出版信息

Ir Vet J. 2020 Jun 16;73:9. doi: 10.1186/s13620-020-00163-1. eCollection 2020.

Abstract

BACKGROUND

There is very little data on the optimal anaesthetic management of ring-tailed lemurs, and the available information is mostly based on extrapolation from other species. In addition, a thorough pre-anaesthetic assessment of lemurs might not be possible without prior chemical immobilization, making a safe immobilization protocol essential.

CASE PRESENTATION

Three ring-tailed lemurs () were immobilized using a combination of intramuscular alfaxalone (5 mg/kg), butorphanol (0.2 mg/kg), and midazolam (0.2 mg/kg), at the University College Dublin Veterinary Hospital. One lemur was anaesthetised once, two lemurs twice, amounting to five anaesthetic events. Conversion to general anaesthesia was warranted in all five occasions, and anaesthesia was maintained with either sevoflurane in oxygen or alfaxalone infusion. The immobilization protocol provided an adequate duration of deep sedation for diagnostic procedures and in some occasions allowed the intubation of the trachea. Analgesia was also provided for minor procedures. No major complications were noted with the protocol used.

CONCLUSIONS

The combination of intramuscular alfaxalone, butorphanol and midazolam provided a clinically useful sedation/immobilization in ring-tailed lemurs with only minor complications such as mild hypothermia, hypotension, hypoventilation and bradycardia. This protocol could be considered in ring-tailed lemurs that need to be immobilized for minor procedures, or as a pre-anaesthetic premedication, especially if a full pre-anaesthetic clinical exam is not possible.

摘要

背景

关于环尾狐猴最佳麻醉管理的数据非常少,现有信息大多基于从其他物种推断而来。此外,在未事先进行化学保定的情况下,可能无法对狐猴进行全面的麻醉前评估,因此安全的保定方案至关重要。

病例报告

都柏林大学学院兽医医院使用肌肉注射阿法沙龙(5毫克/千克)、布托啡诺(0.2毫克/千克)和咪达唑仑(0.2毫克/千克)的组合对三只环尾狐猴进行了保定。一只狐猴接受了一次麻醉,两只狐猴接受了两次麻醉,共计五次麻醉事件。在所有五次情况下都有必要转为全身麻醉,麻醉维持采用氧气中的七氟醚或阿法沙龙输注。保定方案为诊断程序提供了足够时长的深度镇静,在某些情况下还允许进行气管插管。对于小手术也提供了镇痛。所使用的方案未发现重大并发症。

结论

肌肉注射阿法沙龙、布托啡诺和咪达唑仑的组合为环尾狐猴提供了临床上有用的镇静/保定,仅伴有轻度体温过低、低血压、通气不足和心动过缓等轻微并发症。对于需要为小手术进行保定的环尾狐猴,或作为麻醉前的术前用药,尤其是在无法进行全面麻醉前临床检查的情况下,可以考虑采用该方案。

相似文献

2
Alfaxalone anaesthesia in Lemur catta following dexmedetomidine-butorphanol-midazolam sedation.
Vet Anaesth Analg. 2018 May;45(3):351-356. doi: 10.1016/j.vaa.2018.01.004. Epub 2018 Feb 3.
4
Comparison of the efficacy and cardiorespiratory effects of medetomidine-based anesthetic protocols in ring-tailed lemurs (Lemur catta).
J Zoo Wildl Med. 2003 Jun;34(2):163-70. doi: 10.1638/1042-7260(2003)034[0163:COTEAC]2.0.CO;2.
5
Evaluation of modified techniques for immobilization of wild ring-tailed lemurs (Lemur catta).
J Zoo Wildl Med. 2011 Dec;42(4):623-33. doi: 10.1638/2011-0004.1.
9
Rapid Decrease in Populations of Wild Ring-Tailed Lemurs (Lemur catta) in Madagascar.
Folia Primatol (Basel). 2016;87(5):320-330. doi: 10.1159/000455121. Epub 2017 Jan 13.
10
Masseter electromyography during chewing in ring-tailed lemurs (Lemur catta).
Am J Phys Anthropol. 2006 May;130(1):85-95. doi: 10.1002/ajpa.20307.

本文引用的文献

1
Alfaxalone anaesthesia in Lemur catta following dexmedetomidine-butorphanol-midazolam sedation.
Vet Anaesth Analg. 2018 May;45(3):351-356. doi: 10.1016/j.vaa.2018.01.004. Epub 2018 Feb 3.
3
Advancements in Evidence-Based Anesthesia of Exotic Animals.
Vet Clin North Am Exot Anim Pract. 2017 Sep;20(3):917-928. doi: 10.1016/j.cvex.2017.04.014.
7
Evaluation of modified techniques for immobilization of wild ring-tailed lemurs (Lemur catta).
J Zoo Wildl Med. 2011 Dec;42(4):623-33. doi: 10.1638/2011-0004.1.
8
The cardiorespiratory and anesthetic effects of clinical and supraclinical doses of alfaxalone in cats.
Vet Anaesth Analg. 2009 Jan;36(1):42-54. doi: 10.1111/j.1467-2995.2008.00428.x.
9
Cardiorespiratory and anesthetic effects of clinical and supraclinical doses of alfaxalone in dogs.
Vet Anaesth Analg. 2008 Nov;35(6):451-62. doi: 10.1111/j.1467-2995.2008.00406.x. Epub 2008 Sep 11.
10
Biomedical evaluation of free-ranging ring-tailed lemurs (Lemur catta) in three habitats at the Beza Mahafaly Special Reserve, Madagascar.
J Zoo Wildl Med. 2007 Jun;38(2):201-16. doi: 10.1638/1042-7260(2007)038[0201:BEOFRL]2.0.CO;2.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验