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pH 依赖性回肠结肠药物递释系统,第一部分:新型系统的体外和临床评价。

pH-dependent ileocolonic drug delivery, part I: in vitro and clinical evaluation of novel systems.

机构信息

University of Groningen, Groningen Research Institute of Pharmacy, Department of Pharmaceutical Technology and Biopharmacy, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.

University of Groningen, Groningen Research Institute of Pharmacy, Department of Pharmaceutical Technology and Biopharmacy, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.

出版信息

Drug Discov Today. 2020 Aug;25(8):1362-1373. doi: 10.1016/j.drudis.2020.06.011. Epub 2020 Jun 15.

DOI:10.1016/j.drudis.2020.06.011
PMID:32554060
Abstract

After the pH dependency of novel pH-dependent ileocolonic drug delivery systems is confirmed in vitro, their performance should be evaluated in human volunteers.

摘要

在体外确认新型 pH 依赖性回肠结肠药物传递系统的 pH 依赖性后,应在人体志愿者中评估其性能。

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