Reutlingen University, Alteburgstrasse 150, DE-72762 Reutlingen, Germany.
Sony Europe B.V., Stuttgart Technology Center, Hedelfinger Strasse 61, DE-70327 Stuttgart, Germany.
Drug Discov Today. 2020 Sep;25(9):1569-1574. doi: 10.1016/j.drudis.2020.06.002. Epub 2020 Jun 15.
We investigated the state of artificial intelligence (AI) in pharmaceutical research and development (R&D) and outline here a risk and reward perspective regarding digital R&D. Given the novelty of the research area, a combined qualitative and quantitative research method was chosen, including the analysis of annual company reports, investor relations information, patent applications, and scientific publications of 21 pharmaceutical companies for the years 2014 to 2019. As a result, we can confirm that the industry is in an 'early mature' phase of using AI in R&D. Furthermore, we can demonstrate that, despite the efforts that need to be managed, recent developments in the industry indicate that it is worthwhile to invest to become a 'digital pharma player'.
我们调查了人工智能(AI)在药物研发(R&D)中的应用现状,并在此概述了数字 R&D 的风险和回报视角。鉴于该研究领域的新颖性,我们选择了一种定性和定量相结合的研究方法,包括对 21 家制药公司 2014 年至 2019 年的年度公司报告、投资者关系信息、专利申请和科学出版物进行分析。结果表明,该行业正处于在研发中使用 AI 的“早期成熟”阶段。此外,我们还可以证明,尽管需要管理相关投入,但该行业的最新发展表明,投资成为“数字化制药参与者”是值得的。