Trindade Guilherme G, Caxito Samyra M C, Xavier Alessandra Rejane E O, Xavier Mauro A S, BrandÃo Fabiana
University of Brasília, Laboratory of Clinical Microbiology and Immunology, Campus Darcy Ribeiro, Asa Norte, 70910-900 Brasília, DF, Brazil.
AMIL/United Health Group (UHG), 6580, SMAS Trecho 1, Guará, 70211-970 Brasília, DF, Brazil.
An Acad Bras Cienc. 2020 Jun 15;92(2):e20200466. doi: 10.1590/0001-3765202020200466. eCollection 2020.
COVID-19 emerged in December 2019 in China, and since then, has disrupted global public health and changed economic paradigms. In dealing with the new Coronavirus, SARS-CoV-2, the world has not faced such extreme global fragility since the "Spanish flu" pandemic in 1918. Researchers globally are dedicating efforts to the search for an effective treatment for COVID-19. Drugs already used in a clinical setting for other pathologies have been tested as a new therapeutic approach against SARS-CoV-2, setting off a frenzy over the preliminary data of different studies. This work aims to compile and discuss the data published thus far. Despite the potential effects of some antivirals and antiparasitic against COVID-19, clinical studies must confirm real effectiveness. However, non-pharmacological approaches have proven to be the most efficient strategy to date.
2019年12月新型冠状病毒肺炎（COVID-19）在中国出现，自那时起，它扰乱了全球公共卫生并改变了经济模式。在应对新型冠状病毒严重急性呼吸综合征冠状病毒2（SARS-CoV-2）时，自1918年“西班牙流感”大流行以来，世界从未面临过如此极端的全球脆弱性。全球研究人员都在致力于寻找治疗COVID-19的有效方法。已在临床环境中用于其他病症的药物已作为针对SARS-CoV-2的一种新治疗方法进行了测试，引发了对不同研究初步数据的狂热。这项工作旨在汇编和讨论迄今为止发表的数据。尽管一些抗病毒药物和抗寄生虫药物对COVID-19有潜在作用，但临床研究必须证实其实际有效性。然而，迄今为止，非药物方法已被证明是最有效的策略。
