绝经后伊朗女性对停止高血压的饮食方法（DASH）饮食模式和骨质疏松症风险的坚持。
Adherence to the dietary approaches to stop hypertension (DASH) dietary pattern and osteoporosis risk in postmenopausal Iranian women.
机构信息
Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.
Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Islamic Azad University, Karaj Branch, Karaj, Iran.
出版信息
Osteoporos Int. 2020 Nov;31(11):2179-2188. doi: 10.1007/s00198-020-05450-9. Epub 2020 Jun 18.
UNLABELLED
This is the first study to examine the association of adherence to the dietary approaches to stop hypertension (DASH) dietary pattern and osteoporosis risk in postmenopausal Iranian women. Findings suggest the inverse association of adherence to the DASH dietary pattern and osteoporosis risk in postmenopausal Iranian women.
INTRODUCTION
This study was aimed to examine the association of adherence to the dietary approaches to stop hypertension (DASH) dietary pattern and osteoporosis risk in postmenopausal Iranian women, hypothesizing that higher adherence to this pattern is associated with lower risk of postmenopausal osteoporosis.
METHODS
One hundred fifty-one postmenopausal Iranian women aged 50-85 years participated in this cross-sectional study. Lumbar spine and femoral neck bone mineral densities (BMDs) were measured via dual-energy X-ray absorptiometry. Postmenopausal osteoporosis was then defined using the WHO criteria as a BMD T-score of ≤ - 2.5 standard deviations. The usual past-year dietary intakes were assessed by a valid and reliable 168-item food frequency questionnaire. The DASH score was then calculated based on energy-adjusted intakes of eight major dietary components usually emphasized (i.e., fruits, vegetables, nuts and legumes, low-fat dairy products, and whole grains) or minimized (i.e., sodium, sweets, and red or processed meats) in the DASH diet. The higher the DASH score of a participant, the higher the adherence to the DASH dietary pattern.
RESULTS
After adjusting for several potential covariates in the multivariable-adjusted binary logistic regression analysis, participants in the highest tertile of DASH score had lower risk of osteoporosis at lumbar spine than those in the lowest tertile (odds ratio = 0.28; 95% confidence interval, 0.09-0.88; p = 0.029). However, no significant association was observed between adherence to the DASH dietary pattern and risk of osteoporosis at femoral neck.
CONCLUSION
Findings suggest the inverse association of adherence to the DASH dietary pattern and osteoporosis risk in postmenopausal Iranian women.
未加标签
这是第一项研究，旨在探讨坚持高血压饮食防治法（DASH）饮食模式与绝经后伊朗女性骨质疏松风险之间的关联。研究结果表明，坚持 DASH 饮食模式与绝经后伊朗女性骨质疏松风险呈负相关。
引言
本研究旨在探讨坚持高血压饮食防治法（DASH）饮食模式与绝经后伊朗女性骨质疏松风险之间的关联，假设这种模式的高依从性与绝经后骨质疏松风险降低有关。
方法
本横断面研究纳入了 151 名年龄在 50-85 岁之间的绝经后伊朗女性。通过双能 X 射线吸收法测量腰椎和股骨颈骨密度（BMD）。然后，根据世界卫生组织（WHO）标准，将绝经后骨质疏松定义为 BMD T 评分≤-2.5 个标准差。通过一份经过验证和可靠的 168 项食物频率问卷评估过去一年的常规饮食摄入量。然后根据 DASH 饮食中通常强调（即水果、蔬菜、坚果和豆类、低脂乳制品和全谷物）或最小化（即钠、甜食和红色或加工肉类）的八种主要膳食成分的能量调整摄入量计算 DASH 得分。参与者的 DASH 得分越高，其对 DASH 饮食模式的依从性就越高。
结果
在多变量调整后的二元逻辑回归分析中，调整了几个潜在的混杂因素后，DASH 得分最高的 tertile 组的参与者在腰椎处发生骨质疏松的风险低于得分最低的 tertile 组（比值比=0.28；95%置信区间，0.09-0.88；p=0.029）。然而，在股骨颈处，坚持 DASH 饮食模式与骨质疏松风险之间没有显著关联。
结论
研究结果表明，坚持 DASH 饮食模式与绝经后伊朗女性骨质疏松风险呈负相关。
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