Fahimfar Noushin, Hesari Elahe, Mansourzadeh Mohammad Javad, Khalagi Kazem, Sanjari Mahnaz, Hajivalizadeh Sepideh, Tanha Kiarash, Moheimani Hamed, Hajivalizadeh Fatemeh, Irani Amin Doosti, Nematollahi Shahrzad, Larijani Bagher, Ostovar Afshin
Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
J Diabetes Metab Disord. 2023 Nov 30;23(1):229-237. doi: 10.1007/s40200-023-01352-9. eCollection 2024 Jun.
The prevalence of osteoporosis increases as the population ages. The aim of this study was to conduct a systematic review and meta-analysis to estimate the prevalence of osteoporosis among the general population ≥ 50 years old in Iran.
Multiple databases including Scopus, WOS, Medline, Embase, and Persian databases (SID and Magiran) were systematically searched to identify relevant research papers. All population-based studies estimating the prevalence of osteoporosis in the Iranian population were included and imported into Endnote software. Two authors independently reviewed the articles. The Newcastle-Ottawa Scale was used to assess the risk of bias. Statistical analysis was performed using Stata software, and a significance level of 0.05 was applied to the analyses.
Totally 2117 documents were retrieved from the databases up until October 11, 2022. After reading the full texts, 10 documents were included in the study. Our results indicated that the pooled prevalence of osteoporosis in the femoral neck region was 0.19 (95%CI: 0.12-0.26) and 0.19 (95%CI: 0.13-0.25) for women and men, respectively. Pooled prevalence of spinal osteoporosis was 0.29 (95%CI: 0.21-0.38) among women and 0.16 (95%CI: 0.12-0.19) among men. The total pooled prevalence of osteoporosis was 0.38 (95%CI: 0.29-0.48) for women and 0.25 (95%CI: 0.22-0.29) for men.
Our study highlights the elevated prevalence of osteoporosis among individuals aged 50 years and older, with females exhibiting higher rates. Notably, osteoporosis in the femoral neck region demonstrated the lowest prevalence in both sexes. The implementation of comprehensive strategies is imperative to address osteoporosis problems effectively.
The online version contains supplementary material available at 10.1007/s40200-023-01352-9.
骨质疏松症的患病率随着人口老龄化而增加。本研究的目的是进行一项系统评价和荟萃分析，以估计伊朗50岁及以上普通人群中骨质疏松症的患病率。
系统检索了多个数据库，包括Scopus、WOS、Medline、Embase和波斯语数据库（SID和Magiran），以识别相关研究论文。纳入所有估计伊朗人群骨质疏松症患病率的基于人群的研究，并导入Endnote软件。两位作者独立审查文章。采用纽卡斯尔-渥太华量表评估偏倚风险。使用Stata软件进行统计分析，分析的显著性水平为0.05。
截至2022年10月11日，从数据库中总共检索到2117篇文献。阅读全文后，10篇文献纳入本研究。我们的结果表明，女性和男性股骨颈区域骨质疏松症的合并患病率分别为0.19（95%CI：0.12-0.26）和0.19（95%CI：0.13-0.25）。女性脊柱骨质疏松症的合并患病率为0.29（95%CI：0.21-0.38），男性为0.16（95%CI：0.12-0.19）。女性骨质疏松症的总合并患病率为0.38（95%CI：0.29-0.48），男性为0.25（95%CI：0.22-0.29）。
我们的研究强调了50岁及以上人群中骨质疏松症患病率较高，女性患病率更高。值得注意的是，股骨颈区域的骨质疏松症在两性中患病率最低。必须实施综合策略以有效解决骨质疏松症问题。
在线版本包含可在10.1007/s40200-023-01352-9获取的补充材料。
