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评估和治疗强迫性性行为障碍的综合模型。

An integrated model to assess and treat compulsive sexual behaviour disorder.

机构信息

Institute for Sex Research, Sexual Medicine and Forensic Psychiatry, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

出版信息

Nat Rev Urol. 2020 Jul;17(7):391-406. doi: 10.1038/s41585-020-0343-7. Epub 2020 Jun 19.

DOI:10.1038/s41585-020-0343-7
PMID:32561865
Abstract

Contrary to common belief, hypersexual or compulsive sexual behaviour disorder is not a current fashion diagnosis. Nevertheless, the introduction of dedicated diagnostic guidelines for International Classification of Diseases 11th Revision (ICD-11) brings an opportunity for more accurate diagnosis and, therefore, improved research into the disorder's aetiology, assessment and therapy. A considerable proportion of both men and women consider themselves to have a problem with pornography and an even greater proportion experience their sexual behaviour as insufficiently controllable. For these people, the interplay between excitatory and inhibitory factors could be in dysbalance. In this context, biological correlates are important, but social factors, such as negative attitudes towards pornography or hostile attitudes to sexuality, also have a role. In patients with compulsive sexual behaviour disorder, excessive pornography consumption, masturbation and/or promiscuity that are out of control and lead to distress and impairment are usually present. Differential diagnoses, such as neuropsychiatric syndromes that can exhibit hypersexuality as a symptom, such as frontal lobe lesions, should be investigated and treated, as should comorbid disorders such as depression. Therapeutic approaches can be based on the Dual-Control Model and the Sexual Tipping Point Model. In each patient, an individualized therapeutic approach is multimodal and includes psychopharmaceuticals such as selective serotonin reuptake inhibitors and naltrexone as well as specific psychotherapeutic approaches. The efficacy of some therapeutic approaches has now also been supported by initial randomized controlled trials in this patient population.

摘要

与普遍的看法相反,性欲亢进或强迫性性行为障碍并不是当前的时尚诊断。然而,国际疾病分类第 11 版(ICD-11)专门诊断指南的引入为更准确的诊断提供了机会,从而可以更深入地研究该障碍的病因、评估和治疗。相当一部分男性和女性认为自己存在色情问题,甚至更大比例的人认为自己的性行为无法控制。对于这些人来说,兴奋和抑制因素之间的相互作用可能失衡。在这种情况下,生物学相关性很重要,但社会因素,如对色情的负面态度或对性的敌对态度,也有作用。在患有强迫性性行为障碍的患者中,通常存在过度的色情消费、无法控制的自慰和/或滥交,这些会导致痛苦和损伤。应该调查和治疗诸如额叶损伤等可能表现出性欲亢进作为症状的神经精神综合征等鉴别诊断,还应该治疗共病障碍,如抑郁症。治疗方法可以基于双重控制模型和性 tipping 点模型。在每个患者中,个体化的治疗方法是多模式的,包括选择性 5-羟色胺再摄取抑制剂和纳曲酮等精神药物以及特定的心理治疗方法。一些治疗方法的疗效现已在该患者群体的初步随机对照试验中得到支持。

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