Division of Cardiovascular Surgery, Saitama Medical University International Medical Center, 1397-1, Yamane, Hidaka, Saitama, 3501298, Japan.
Gen Thorac Cardiovasc Surg. 2021 Jan;69(1):1-7. doi: 10.1007/s11748-020-01408-0. Epub 2020 Jun 19.
The optimal surgical strategy for atrial functional mitral regurgitation remains uncertain. Preoperative mitral-septal angle ≤ 70° has been reported as a risk factor for an abnormal vortex pattern in mitral valve repair. This study aimed to elucidate the change in the mitral-septal angle after surgery for atrial functional mitral regurgitation and its effect on the mid-term outcomes.
Forty patients underwent mitral valve repair for atrial functional mitral regurgitation. The mitral-septal angle was defined as the angle between the mitral annulus and the anteroseptal wall of the left ventricular mid-portion in the parasternal long-axis view on transthoracic echocardiography. All patients underwent mitral ring annuloplasty. Left atrial plication was performed in nine patients. The mean clinical follow-up period was 42 ± 24 months.
The ratio of left atrial volume to left ventricular end-systolic volume was negatively correlated with the preoperative mitral-septal angle. The postoperative mitral-septal angles were significantly smaller than the preoperative ones. The mitral-septal angle decreased with a decrease in the mitral annuloplasty ring size. Patients who underwent left atrial plication tended to show an increase in the mitral-septal angle postoperatively. There were no significant differences in mid-term morbidities, including heart failure, requiring re-hospitalization and mortalities between patients with postoperative MSA > 70° and those with postoperative MSA ≤ 70°.
Mitral ring annuloplasty negatively changed the mitral-septal angle, while left atrial plication may induce a positive change to the mitral-septal angle. An association between the mitral-septal angle and mid-term outcomes was not revealed in this study.
对于左心房功能性二尖瓣反流,最佳的手术策略仍不确定。术前二尖瓣-隔瓣夹角≤70°已被报道为二尖瓣修复术中异常涡流模式的危险因素。本研究旨在阐明左心房功能性二尖瓣反流患者手术后二尖瓣-隔瓣夹角的变化及其对中期结果的影响。
40 例患者因左心房功能性二尖瓣反流而行二尖瓣修复术。在经胸超声心动图的胸骨旁长轴切面中,二尖瓣-隔瓣夹角定义为二尖瓣环与左心室中段前间隔壁之间的夹角。所有患者均行二尖瓣环成形术。9 例患者行左心房折叠术。平均临床随访时间为 42±24 个月。
左心房容积与左心室收缩末期容积的比值与术前二尖瓣-隔瓣夹角呈负相关。术后二尖瓣-隔瓣夹角明显小于术前。二尖瓣-隔瓣夹角随二尖瓣环成形环尺寸的减小而减小。行左心房折叠术的患者术后二尖瓣-隔瓣夹角有增大趋势。术后二尖瓣-隔瓣夹角>70°与术后二尖瓣-隔瓣夹角≤70°的患者中期发病率,包括心力衰竭、再住院和死亡率,差异均无统计学意义。
二尖瓣环成形术可使二尖瓣-隔瓣夹角发生负性改变,而左心房折叠术可能使二尖瓣-隔瓣夹角发生正性改变。本研究未发现二尖瓣-隔瓣夹角与中期结果之间存在关联。