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中国大陆首例利奈唑胺致儿童牙齿着色。

The first case of teeth discoloration induced by linezolid in children in China Mainland.

机构信息

Department of Pharmacy, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, China.

Department of Traumatic Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, China.

出版信息

J Infect Chemother. 2020 Oct;26(10):1062-1065. doi: 10.1016/j.jiac.2020.05.010. Epub 2020 Jun 17.

Abstract

Linezolid is an oxazolidinone antimicrobial agent often used to treat multidrug-resistant Gram-positive bacterial infections. The common adverse reactions of linezolid are diarrhea, nausea, headache and bone marrow suppression, and so on. Here, we report the first case of teeth discoloration induced by linezolid linked with extrinsic discoloration in China Mainland. This case report highlights a rare adverse reactions of a commonly used antibiotic.

摘要

利奈唑胺是一种恶唑烷酮类抗菌药物,常被用于治疗多种耐药革兰阳性菌感染。利奈唑胺的常见不良反应包括腹泻、恶心、头痛和骨髓抑制等。在这里,我们报告了中国大陆首例与外源性着色相关的利奈唑胺引起的牙齿着色病例。本病例报告强调了一种常用抗生素的罕见不良反应。

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