Brazilian National Cancer Institute, Rio de Janeiro, Brazil; Grupo Oncoclínicas, Rio de Janeiro, Brazil.
Brazilian National Cancer Institute, Rio de Janeiro, Brazil; Grupo Oncoclínicas, Rio de Janeiro, Brazil.
Crit Rev Oncol Hematol. 2020 Sep;153:103016. doi: 10.1016/j.critrevonc.2020.103016. Epub 2020 Jun 9.
For many decades, the Bokhman dualist vision was used to stratify endometrial cancer (EC) in good or bad tumors. Nowadays, a more robust and reliable molecular stratification is taking place with the The Cancer Genome Atlas Research Network (TCGA) classification bringing new and important information in the field. Collaborative groups are replicating TCGA using accessible tools with immunohistochemistry. It's time to move on and include this information along with pathology features to better delineate adjuvant treatment in EC.
几十年来，博克曼二元论观点一直被用于对子宫内膜癌（EC）进行良性或恶性肿瘤的分层。如今，随着癌症基因组图谱研究网络（TCGA）分类的出现，一种更强大、更可靠的分子分层正在进行，为该领域带来了新的重要信息。协作组正在使用免疫组织化学方法复制 TCGA 可用的工具。是时候将这些信息与病理特征一起纳入，以更好地描绘 EC 的辅助治疗了。
