Botswana National Veterinary Laboratory, Private Bag 0035, Gaborone, Botswana.
Animal Production and Health Laboratory, Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Wagramer Strasse 5, P.O. Box 100, 1400, Vienna, Austria.
Virus Genes. 2020 Oct;56(5):646-650. doi: 10.1007/s11262-020-01770-4. Epub 2020 Jun 20.
Avian paramyxovirus-1 (APMV-1), the causative agent of Newcastle disease (ND) in domestic and wild avian species, has recently been reported and characterized in five southern African countries (i.e. Mozambique, Namibia, South Africa, Zambia and Zimbabwe). Since APMV-1s have never been characterized in Botswana, this study was undertaken to determine the genotype circulating in the country. Fourteen samples were collected from ND outbreaks in poultry in 2014, 2018 and 2019 and the complete fusion protein gene was sequenced. Phylogenetic analysis revealed that all of the viruses from Botswana clustered in genotype VII.2 (previously subgenotype VIIh) and that they were more related to viruses from South Africa and Mozambique than the other southern African countries (i.e. Namibia, Zambia and Zimbabwe).
禽副黏病毒 1 型（APMV-1）是引起家禽和野生鸟类新城疫（ND）的病原体，最近在 5 个南部非洲国家（莫桑比克、纳米比亚、南非、赞比亚和津巴布韦）被报道和鉴定。由于博茨瓦纳从未鉴定过 APMV-1，因此进行了本研究以确定该国流行的基因型。从 2014 年、2018 年和 2019 年家禽 ND 暴发中采集了 14 个样本，并对完整的融合蛋白基因进行了测序。系统进化分析表明，博茨瓦纳的所有病毒均聚类在基因型 VII.2（以前的 subgenotype VIIh），与南非和莫桑比克的病毒关系更为密切，而与其他南部非洲国家（纳米比亚、赞比亚和津巴布韦）的病毒关系较远。
