Laboratoire Central de l'Elevage (LABOCEL), Niamey, Niger.
Université de Tillabéri, Tillabéri, Niger.
Virus Genes. 2021 Feb;57(1):100-105. doi: 10.1007/s11262-020-01804-x. Epub 2020 Oct 31.
The causative agent of Newcastle disease (ND) of poultry is the avian paramyxovirus-1, also commonly known as ND virus (NDV). Like in many developing countries, ND is endemic in Niger and has significant economic impact on commercial and backyard poultry production. NDVs were characterized in Niger between 2006 and 2008 and shown to belong to genotypes XIV.1 and XVII. In order to determine the current situation regarding the virus in Niger, tracheas (n = 384) were collected for the detection of NDV from both healthy (n = 335) and sick (n = 49) backyard poultry in 2019. Of these samples, 24 from sick chickens were positive for NDV by conventional RT-PCR. Sequencing of the fusion protein gene and phylogenetic analysis revealed that the viruses belonged to either genotype XIV.2 or XVIII.2. No NDVs of genotype XIV.1 or XVII were identified in the current study highlighting the dynamic nature of NDV circulation in Niger and the region.
家禽新城疫（ND）的病原体是禽副黏病毒-1，也通常称为 ND 病毒（NDV）。与许多发展中国家一样，尼日尔也存在 ND，这对商业和后院家禽生产造成了重大的经济影响。2006 年至 2008 年间，在尼日尔对 NDV 进行了特征描述，结果表明其属于基因型 XIV.1 和 XVII。为了确定尼日尔目前的病毒情况，2019 年从健康（n=335）和患病（n=49）后院家禽中采集了 384 个气管样本，以检测 NDV。其中，24 份来自患病鸡的样本通过常规 RT-PCR 检测为 NDV 阳性。融合蛋白基因的测序和系统发育分析表明，这些病毒属于基因型 XIV.2 或 XVIII.2。在本研究中未鉴定到基因型 XIV.1 或 XVII 的 NDV，这突出了 ND 在尼日尔和该地区的动态循环特性。
