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从急性疼痛到持续性疼痛的转变:在急诊科就诊的女性中,不同轨迹的识别。

The transition from acute to persistent pain: the identification of distinct trajectories among women presenting to an emergency department.

机构信息

Rush University Medical Center, Chicago, IL, United States.

Vanderbilt University Medical Center, Nashville, TN, United States.

出版信息

Pain. 2020 Nov;161(11):2511-2519. doi: 10.1097/j.pain.0000000000001960.

Abstract

Posttraumatic stress disorder (PTSD) symptoms and other negative psychosocial factors have been implicated in the transition from acute to persistent pain. Women (N = 375) who presented to an inner-city emergency department (ED) with complaints of acute pain were followed up for 3 months. They completed a comprehensive battery of questionnaires at an initial visit and provided ratings of pain intensity at the site of pain presented in the ED during 3 monthly phone calls. Latent class growth analyses were used to detect possible trajectories of change in pain intensity from the initial visit to 3 months later. A 3-trajectory solution was found, which identified 3 groups of participants. One group (early recovery; n = 93) had recovered to virtually no pain by the initial visit, whereas a second group (delayed recovery; n = 120) recovered to no pain only after 1 month. A third group (no recovery; n = 162) still reported elevated pain at 3 months after the ED visit. The no recovery group reported significantly greater PTSD symptoms, anger, sleep disturbance, and lower social support at the initial visit than both the early recovery and delayed recovery groups. Results suggest that women with high levels of PTSD symptoms, anger, sleep disturbance, and low social support who experience an acute pain episode serious enough to prompt an ED visit may maintain elevated pain at this pain site for at least 3 months. Such an array of factors may place women at an increased risk of developing persistent pain following acute pain.

摘要

创伤后应激障碍(PTSD)症状和其他负面心理社会因素与急性疼痛向持续性疼痛的转变有关。有急性疼痛症状的女性(N=375)到市区急诊室就诊,在接下来的 3 个月内进行了随访。她们在初次就诊时完成了一系列综合问卷,并在 3 个月的电话随访中对急诊室就诊时疼痛部位的疼痛强度进行了评分。使用潜在类别增长分析来检测从初次就诊到 3 个月后疼痛强度变化的可能轨迹。发现了 3 个轨迹解决方案,确定了 3 组参与者。一组(早期恢复;n=93)在初次就诊时已基本无疼痛,而另一组(延迟恢复;n=120)仅在 1 个月后才恢复无疼痛。第三组(无恢复;n=162)在 ED 就诊后 3 个月仍报告疼痛明显升高。与早期恢复组和延迟恢复组相比,无恢复组在初次就诊时报告 PTSD 症状、愤怒、睡眠障碍和社会支持较低的症状显著更高。结果表明,在 ED 就诊时经历了足以引起 ED 就诊的严重急性疼痛发作且 PTSD 症状、愤怒、睡眠障碍和社会支持较低的女性,在该疼痛部位的疼痛至少可能持续 3 个月。这种多种因素的组合可能会使女性在急性疼痛后发生持续性疼痛的风险增加。

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