用于人体旋毛虫病血清学诊断的标准酶联免疫吸附测定法（ELISA）与斑点酶联免疫吸附测定法（dot-ELISA）的比较
Comparison between standard ELISA and dot-ELISA for serodiagnosis of human trichinosis.
作者信息
Chan S W, Ko R C
机构信息
Department of Zoology, University of Hong Kong.
出版信息
Trans R Soc Trop Med Hyg. 1988;82(6):892-4. doi: 10.1016/0035-9203(88)90030-2.
PMID:3256992
Abstract
The dot enzyme-linked immunosorbent assay (dot-ELISA) provided rapid and accurate detection of human trichinosis. Comparable sensitivity and specificity of the standard ELISA and dot-ELISA were obtained when sera of 18 confirmed cases of trichinosis were screened. Cross-reactivity was assayed with sera from 31 Chinese subjects with other parasitic infections. Only 2 cross-reactions occurred in the dot-ELISA, compared with 7 in the standard ELISA.
摘要
斑点酶联免疫吸附测定（dot-ELISA）可快速、准确地检测人体旋毛虫病。用18例旋毛虫病确诊病例的血清进行筛查时，标准ELISA和dot-ELISA的敏感性和特异性相当。用31例患有其他寄生虫感染的中国受试者的血清检测交叉反应性。dot-ELISA仅出现2次交叉反应，而标准ELISA出现7次。
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