Morsy T A, Schnur L F, Feinsod F M, Michael S A, Saah A, Salama M M, Wahba M M
Ain Shams Research and Training Center of Vectors of Diseases, Ain Shams University, Cairo, Egypt.
Ann Trop Med Parasitol. 1988 Oct;82(5):437-44. doi: 10.1080/00034983.1988.11812273.
A survey of rodents and dogs was carried out in Alexandria and its environs to see if an animal reservoir was associated with an outbreak of infantile kala-azar in this area. Three rodent species, Rattus rattus, Rattus norvegicus and Mus musculus, were commonly trapped and examined. A flagellate parasite was isolated from the spleens of two R. norvegicus. It was typed serologically by excreted factor serotyping and enzymologically by thick starch electrophoresis of four of its enzymes: GPI, G6PD, 6PGD and PGM. The same type of parasite was also isolated from two stray dogs from the same vicinity. This flagellate was quite distinct from Leishmania donovani, Leishmania major and Leishmania tropica, the three common Old World species of Leishmania; but its exact identity remains uncertain. It could be a new leishmanial entity or a flagellate parasite of another genus.
在亚历山大及其周边地区对啮齿动物和狗进行了一项调查，以确定动物宿主是否与该地区婴儿黑热病的爆发有关。共捕获并检查了三种啮齿动物，即黑家鼠、褐家鼠和小家鼠。从两只褐家鼠的脾脏中分离出一种鞭毛虫寄生虫。通过排泄因子血清分型对其进行血清学分型，并通过对其四种酶（GPI、G6PD、6PGD和PGM）进行厚淀粉凝胶电泳进行酶学分型。在同一地区的两只流浪狗身上也分离出了相同类型的寄生虫。这种鞭毛虫与利什曼原虫属的三种常见的旧世界物种——杜氏利什曼原虫、硕大利什曼原虫和热带利什曼原虫截然不同；但其确切身份仍不确定。它可能是一种新的利什曼原虫实体，也可能是另一个属的鞭毛虫寄生虫。
