Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Rd, Shanghai, China.
Clinical Centre for Sleep Breathing Disorders and Snoring, Zhongshan Hospital, Fudan University, Shanghai, China.
Respir Res. 2020 Jun 22;21(1):156. doi: 10.1186/s12931-020-01404-1.
Clinical questionnaires are mainly applied as screening tools for identification of the Obstructive sleep apnea (OSA) patients. Little attention has been paid to assess the body functions and health status of the patients. International Classification of Functioning, Disability and Health (ICF) was designed for better understanding and describing functioning and disability of patients. This study adopted the Brief ICF-Sleep Disorders and Obesity Core Set to evaluate the impairment of functioning and health status of OSA patients.
Five hundred ninety-two participants were enrolled in this cross-sectional study. Data were collected using Brief ICF-Sleep Disorders and Obesity Core Set Polysomnography was performed and basic characteristics of the patients were recorded.
The scores for the component Body Functions and Code b130, b134, b140, b440, b530, s330, d160, d240, d450 of the two core sets were significantly different among the patients divided by apnea-hypopnea index (AHI) or oxygen saturation (SaO2) nadir, but the frequency of code s330, d160, d240, d450 was low. The Body Functions component of the both sets were closely related to neck circumference (NC), body mass index (BMI), apnea-hypopnea index (AHI) of the OSA patients. Body Functions of the Brief ICF-Sleep Disorders performed better with a threshold of 4 with sensitivity, specificity and area under the receiver operating characteristic curve (AUC) as 0.62, 0.74, 0.68(AHI ≥ 5), 0.69, 0.63, 0.66 (AHI ≥ 15), 0.75, 0.56, 0.66 (AHI ≥ 30), 0.56, 0.70, 0.63 (SaO2 nadir≤90%), 0.67, 0.66, 0.66 (SaO2 nadir<85%), 0.71, 0.59, 0.65 (SaO2 nadir<80%), separately.
The Body Functions component of both two sets could be an evaluation tool of impairment of body functions for OSA patients. The Brief ICF-Sleep Disorders Body Functions component performed better with a threshold of 4 and might provide a new insight for physicians to assess OSA patients.
临床问卷主要作为识别阻塞性睡眠呼吸暂停（OSA）患者的筛查工具。很少关注评估患者的身体功能和健康状况。《国际功能、残疾和健康分类》（ICF）旨在更好地理解和描述患者的功能和残疾。本研究采用简短 ICF-睡眠障碍和肥胖核心组来评估 OSA 患者的功能障碍和健康状况。
本横断面研究共纳入 592 名参与者。使用简短 ICF-睡眠障碍和肥胖核心组收集数据，进行多导睡眠图检查，并记录患者的基本特征。
根据呼吸暂停-低通气指数（AHI）或最低血氧饱和度（SaO2）将患者分为不同亚组后，两组核心组的身体功能和代码 b130、b134、b140、b440、b530、s330、d160、d240、d450 分量的得分存在显著差异，但代码 s330、d160、d240、d450 的出现频率较低。两组的身体功能成分与颈围（NC）、体重指数（BMI）、OSA 患者的呼吸暂停-低通气指数（AHI）密切相关。简短 ICF-睡眠障碍的身体功能表现更好，其阈值为 4，灵敏度、特异性和受试者工作特征曲线下面积（AUC）分别为 0.62、0.74、0.68（AHI≥5）、0.69、0.63、0.66（AHI≥15）、0.75、0.56、0.66（AHI≥30）、0.56、0.70、0.63（SaO2 最低值≤90%）、0.67、0.66、0.66（SaO2 最低值<85%）、0.71、0.59、0.65（SaO2 最低值<80%）。
两组的身体功能成分都可以作为 OSA 患者身体功能障碍的评估工具。简短 ICF-睡眠障碍的身体功能成分在阈值为 4 时表现更好，可能为医生评估 OSA 患者提供新的思路。
