Zong Ya-Wen, Cheng Lei, Guo Qiang, Zhou Xue-Dong, Ren Biao
State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Hua Xi Kou Qiang Yi Xue Za Zhi. 2020 Jun 1;38(3):319-323. doi: 10.7518/hxkq.2020.03.016.
Phenolic compounds are widely found in natural Chinese medicinal plants and have excellent pharmacological properties, such as antioxidation and anti-inflammation. They are the main pharmacological components of many medicinal Chinese herbs. Oral microbiota, especially its composition and metabolism, is highly related to the balance of oral microecology and plays a key role in the occurrence and development of oral diseases. Recent studies have shown that phenolic compounds of traditional Chinese herbs can prevent and treat oral diseases, such as caries, periodontal disease, and oral mucosal infection, by regulating the composition, metabolites, and virulence of oral microorganisms. This review will summarize and discuss the regulation of phenolic compounds on oral microbes.
酚类化合物广泛存在于天然中药材中,具有抗氧化、抗炎等优异的药理特性。它们是许多中草药的主要药理成分。口腔微生物群,尤其是其组成和代谢,与口腔微生态平衡高度相关,在口腔疾病的发生和发展中起关键作用。最近的研究表明,中草药中的酚类化合物可通过调节口腔微生物的组成、代谢产物和毒力来预防和治疗龋齿、牙周病和口腔黏膜感染等口腔疾病。本文综述并讨论酚类化合物对口腔微生物的调节作用。