Słomka Artur, Kowalewski Mariusz, Żekanowska Ewa
Department of Pathophysiology, Nicolaus Copernicus University in Toruń, Ludwik Rydygier Collegium Medicum, 85-094 Bydgoszcz, Poland.
Clinical Department of Cardiac Surgery, Central Clinical Hospital of the Ministry of Interior and Administration, Centre of Postgraduate Medical Education, 02-607 Warsaw, Poland.
Pathogens. 2020 Jun 20;9(6):493. doi: 10.3390/pathogens9060493.
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a rapidly spreading and devastating global pandemic. Many researchers are attempting to clarify the mechanisms of infection and to develop a drug or vaccine against the virus, but there are still no proven effective treatments. The present article reviews the common presenting hematological manifestations of coronavirus disease 2019 (COVID-19). Elucidating the changes in hematological parameters in SARS-CoV-2 infected patients could help to understand the pathophysiology of the disease and may provide early clues to diagnosis. Several studies have shown that hematological parameters are markers of disease severity and suggest that they mediate disease progression.
感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2）是一场迅速蔓延且极具破坏性的全球大流行。许多研究人员正试图阐明感染机制并研发针对该病毒的药物或疫苗，但目前仍没有经证实有效的治疗方法。本文综述了2019冠状病毒病（COVID-19）常见的血液学表现。阐明SARS-CoV-2感染患者血液学参数的变化有助于理解该疾病的病理生理学，并可能为诊断提供早期线索。多项研究表明，血液学参数是疾病严重程度的标志物，并提示它们介导疾病进展。
