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一只家养长毛猫的鼻内增殖性纤维-骨发育异常

Intranasal proliferative fibro-osseous dysplasia in a domestic longhair cat.

作者信息

D'Aout Clarisse, Renfrew Helen, Dobromylskyj Melanie, Bacon Nicholas, Herrmann Annika, Taylor Samantha S

机构信息

Lumbry Park Veterinary Specialists, Alton, UK.

Finn Pathologists Histopathology Department, Diss, Norfolk, UK.

出版信息

JFMS Open Rep. 2020 Jun 10;6(1):2055116920917839. doi: 10.1177/2055116920917839. eCollection 2020 Jan-Jun.

Abstract

CASE SUMMARY

A 13-year-old female domestic longhair cat was presented for further investigation of chronic sneezing combined with a right-sided nasal discharge. A CT scan of the head revealed a locally invasive, aggressive right nasal mass radiographically consistent with a malignant neoplastic process. Histopathology on rhinoscopically guided biopsies revealed an unusual pathology consistent with fibro-osseous hyperplasia/dysplasia. Surgical treatment via a ventral rhinotomy and curettage was performed, and the diagnosis confirmed by repeat histopathology. The cat's clinical signs significantly improved postoperatively.

RELEVANCE AND NOVEL INFORMATION

This case report describes an unusual feline nasal pathology. To our knowledge, there are no previous reports of a non-neoplastic, non-inflammatory expansile feline nasal tumour. Also described are the CT and histological appearance of the mass, and the difficulties encountered obtaining the definitive diagnosis. Information regarding the prognosis following surgical removal of proliferative fibro-osseous lesions in cats is poor, especially from the nasal cavity where clean margins may well be impossible to obtain. In this case, surgical resection improved clinical signs and the cat remains well at 15 months post-procedure.

摘要

病例摘要

一只13岁的雌性家养长毛猫因慢性打喷嚏并伴有右侧鼻腔分泌物而前来进一步检查。头部CT扫描显示右侧鼻腔有一个局部侵袭性、生长迅速的肿物,影像学表现与恶性肿瘤过程一致。经鼻镜引导活检的组织病理学检查显示为一种不寻常的病理表现,符合纤维性骨增生/发育异常。通过腹侧鼻切开术和刮除术进行了手术治疗,并通过重复组织病理学检查确诊。这只猫的临床症状在术后明显改善。

相关性和新信息

本病例报告描述了一种不寻常的猫鼻腔病理情况。据我们所知,此前没有关于非肿瘤性、非炎性的猫鼻腔扩张性肿物的报道。文中还描述了肿物的CT和组织学表现,以及在获得明确诊断过程中遇到的困难。关于猫鼻腔增殖性纤维性骨病变手术切除后的预后信息很少,尤其是在鼻腔难以获得切缘阴性的情况下。在本病例中,手术切除改善了临床症状,术后15个月这只猫状况良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18cc/7288824/46a750da69ba/10.1177_2055116920917839-fig1.jpg

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