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Hyperferritinemia in critically ill COVID-19 patients - Is ferritin the product of inflammation or a pathogenic mediator?

作者信息

Gómez-Pastora Jenifer, Weigand Mitchell, Kim James, Wu Xian, Strayer Jacob, Palmer Andre F, Zborowski Maciej, Yazer Mark, Chalmers Jeffrey J

机构信息

William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, 151 West Woodruff Avenue, Columbus, OH 43210, United States.

Department of Biomedical Engineering, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, United States.

出版信息

Clin Chim Acta. 2020 Oct;509:249-251. doi: 10.1016/j.cca.2020.06.033. Epub 2020 Jun 21.

DOI:10.1016/j.cca.2020.06.033
PMID:32579952
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7306200/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6168/7306200/096e3ae7deac/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6168/7306200/096e3ae7deac/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6168/7306200/096e3ae7deac/gr1_lrg.jpg

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本文引用的文献

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EMBO Mol Med. 2020 Jul 7;12(7):e12421. doi: 10.15252/emmm.202012421. Epub 2020 Jun 5.
2
Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients.SARS-CoV-2 感染患者外周血淋巴细胞反应和细胞因子谱的纵向特征。
EBioMedicine. 2020 May;55:102763. doi: 10.1016/j.ebiom.2020.102763. Epub 2020 Apr 18.
3
Clinical and immunological features of severe and moderate coronavirus disease 2019.
ANE-SS联合铁蛋白和DIC评分对急性坏死性脑病患儿死亡风险的预测价值
Transl Pediatr. 2025 Jan 24;14(1):42-51. doi: 10.21037/tp-24-416. Epub 2025 Jan 21.
4
The recombinant spike S1 protein induces injury and inflammation in co-cultures of human alveolar epithelial cells and macrophages.重组刺突S1蛋白在人肺泡上皮细胞和巨噬细胞共培养物中诱导损伤和炎症。
PLoS One. 2025 Feb 10;20(2):e0318881. doi: 10.1371/journal.pone.0318881. eCollection 2025.
5
Taurolithocholic acid protects against viral haemorrhagic fever via inhibition of ferroptosis.牛磺胆酸通过抑制铁死亡来预防病毒性出血热。
Nat Microbiol. 2024 Oct;9(10):2583-2599. doi: 10.1038/s41564-024-01801-y. Epub 2024 Sep 18.
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Curr Med Chem. 2025;32(16):3134-3154. doi: 10.2174/0109298673301578240515095227.
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Heliyon. 2024 May 10;10(10):e30955. doi: 10.1016/j.heliyon.2024.e30955. eCollection 2024 May 30.
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