Division of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, Aghia Sophia Children's Hospital, Athens, Greece,
Division of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, Aghia Sophia Children's Hospital, Athens, Greece.
Horm Res Paediatr. 2020;93(2):94-107. doi: 10.1159/000507760. Epub 2020 Jun 24.
Obesity in childhood and adolescence represents a major health problem of our century. In Greece, 30-35% of children and adolescents are overweight or obese. Objective and Hypotheses: To investigate the effectiveness of a comprehensive multidisciplinary personalized management plan at reducing the prevalence of overweight and obesity in childhood and adolescence.
One thousand (n = 1,000) children and adolescents aged 2-18 years (mean age ± SD: 10.09 ± 2.86 years; 520 females, 480 males) were studied prospectively. Subjects were classified as obese (n = 579, 57.9%), overweight (n = 295, 29.5%) or having a normal body mass index (BMI) (n = 126, 12.6%) according to the International Obesity Task Force cutoff points. All subjects were evaluated by a multidisciplinary team at frequent intervals, received personalized advice on diet and exercise and were studied prospectively for 1 year. Detailed clinical evaluation and laboratory investigations were performed at the beginning and at the end of the study.
At initial evaluation, 57.9% of subjects were obese, 29.5% overweight and 12.6% of normal BMI. Indices of cardiometabolic disease were higher in obese than in overweight and normal-BMI subjects. Following 1 year of multidisciplinary management interventions, the prevalence of obesity decreased by 16.8%, the prevalence of normal BMI increased by 8.2%, and all cardiometabolic indices improved significantly.
A personalized multidisciplinary management plan is effective at reducing the prevalence of obesity in childhood and adolescence.
儿童和青少年肥胖是我们这个世纪的一个主要健康问题。在希腊，有 30-35%的儿童和青少年超重或肥胖。目的和假设：研究一种综合的多学科个性化管理计划在降低儿童和青少年超重和肥胖患病率方面的有效性。
我们前瞻性研究了 1000 名 2-18 岁的儿童和青少年（平均年龄 ± SD：10.09 ± 2.86 岁；520 名女性，480 名男性）。根据国际肥胖工作组的切点，将患者分为肥胖组（n = 579，57.9%）、超重组（n = 295，29.5%）或正常体重指数组（n = 126，12.6%）。所有患者均由多学科团队定期评估，接受饮食和运动的个性化建议，并前瞻性研究 1 年。在研究开始和结束时进行详细的临床评估和实验室检查。
在初始评估时，57.9%的患者肥胖，29.5%超重，12.6%的患者正常体重指数。肥胖患者的心血管代谢疾病指数高于超重和正常体重指数患者。经过 1 年的多学科管理干预，肥胖患病率下降了 16.8%，正常体重指数患病率上升了 8.2%，所有心血管代谢指数均显著改善。
个性化的多学科管理计划可有效降低儿童和青少年肥胖的患病率。
