调节牛蛙的耳朵。
Tuning in the bullfrog ear.
作者信息
Lewis E R
机构信息
Electronics Research Laboratory, University of California, Berkeley 94720.
出版信息
Biophys J. 1988 Mar;53(3):441-7. doi: 10.1016/S0006-3495(88)83120-5.
Abstract
When electrical resonances were observed in acoustic sensory cells of lower vertebrates, the hearing research community was presented with the exciting possibility that tuning in the ears of those animals might be explained directly in terms of familiar molecular devices. It is reported here that in the frog sacculus, where electrical resonances have been observed in isolated hair cells, the effects of those resonances are completely obscured in the tuning properties of the sacculus in the intact ear. This observation has important implications not only for students of the ear, but for reductionist biologists in general. All of the dynamic properties of a system of connected, bidirectional processes are consequences of all of those processes at once; in such a system, the properties of an experimentally isolated subsystem may be totally obscured in the operation of the system as a whole.
摘要
当在低等脊椎动物的听觉感觉细胞中观察到电共振时，听力研究界面临着一个令人兴奋的可能性，即这些动物耳朵中的调谐可能直接用熟悉的分子装置来解释。本文报道，在青蛙的球囊（已在分离的毛细胞中观察到电共振）中，这些共振的效应在完整耳朵中球囊的调谐特性中完全被掩盖。这一观察结果不仅对耳朵研究人员，而且对一般的还原论生物学家都具有重要意义。一个由相互连接的双向过程组成的系统的所有动态特性，都是所有这些过程同时作用的结果；在这样一个系统中，实验分离的子系统的特性在整个系统的运行中可能会被完全掩盖。
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本文引用的文献
1
Studies with artificial neurons. III. Mechanisms of flicker-fusion.人工神经元研究。III. 闪烁融合机制。
Kybernetik. 1961 Dec;1:107-17. doi: 10.1007/BF00290181.
2
STATISTICAL ANALYSIS OF THE DARK DISCHARGE OF LATERAL GENICULATE NEURONES.外侧膝状体神经元暗放电的统计分析
J Physiol. 1964 Apr;170(3):598-612. doi: 10.1113/jphysiol.1964.sp007352.
3
The frequency selectivity of auditory nerve fibres and hair cells in the cochlea of the turtle.乌龟耳蜗中听觉神经纤维和毛细胞的频率选择性。
J Physiol. 1980 Sep;306:79-125. doi: 10.1113/jphysiol.1980.sp013387.
4
Cochlear mechanics: nonlinear behavior in two-tone responses as reflected in cochlear-nerve-fiber responses and in ear-canal sound pressure.耳蜗力学：两音反应中的非线性行为，如在耳蜗神经纤维反应和耳道声压中所反映的那样。
J Acoust Soc Am. 1980 May;67(5):1704-21. doi: 10.1121/1.384297.
5
An electrical tuning mechanism in turtle cochlear hair cells.龟耳蜗毛细胞中的电调谐机制。
J Physiol. 1981 Mar;312:377-412. doi: 10.1113/jphysiol.1981.sp013634.
6
Bidirectional transduction in vertebrate hair cells: a mechanism for coupling mechanical and electrical processes.脊椎动物毛细胞中的双向转导：一种机械过程与电过程耦合的机制。
Hear Res. 1982 Aug;7(3):353-60. doi: 10.1016/0378-5955(82)90045-4.
7
Acute seismic sensitivity in the bullfrog ear.牛蛙耳部的急性地震敏感性。
Brain Res. 1982 Oct 28;250(1):168-72. doi: 10.1016/0006-8993(82)90964-7.
8
Inner ear: dye injection reveals peripheral origins of specific sensitivities.内耳：染料注射揭示了特定敏感性的外周起源。
Science. 1982 Mar 26;215(4540):1641-3. doi: 10.1126/science.6978525.
9
Kinetics of the receptor current in bullfrog saccular hair cells.牛蛙球囊毛细胞中受体电流的动力学
J Neurosci. 1983 May;3(5):962-76. doi: 10.1523/JNEUROSCI.03-05-00962.1983.
10
Neurophysiological evidence for a traveling wave in the amphibian inner ear.两栖类内耳中行波的神经生理学证据。
Science. 1984 Sep 7;225(4666):1037-9. doi: 10.1126/science.6474164.
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