von Zimmermann Claudia, Winkelmann Merle, Richter-Schmidinger Tanja, Mühle Christiane, Kornhuber Johannes, Lenz Bernd
Department of Psychiatry and Psychotherapy, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.
Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health (CIMH), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Front Psychiatry. 2020 Jun 5;11:494. doi: 10.3389/fpsyt.2020.00494. eCollection 2020.
Physical activity and a healthy body composition are said to reduce the risk of major depressive disorder. Nonetheless, deeper insight is needed into which specific forms of physical activity (and their relation to body composition) are effective in improving and preventing depressive symptoms.
We compared different self-reported physical activities of the Global Physical Activity Questionnaire and body composition measures between patients with a current major depressive episode (MDE; = 130) and healthy control subjects ( = 61). These parameters were also tested for correlations with depression severity and serum lipid levels in patients and controls.
Patients with a current MDE reported significantly fewer hours spent on total physical activity, walking or bicycling for travel, and vigorous-intensity activities at leisure than healthy control subjects. More time spent on vigorous-intensity activities at work, less time spent on walking or bicycling for travel, higher body fat mass, and lower body muscle mass correlated significantly with stronger depression severity. Physical activity and body measures correlated significantly with serum lipid levels.
Self-reports of physical activity, only short-term follow-up of 20 days, cross-sectional study design without examination of causal role of exercise.
More time spent on traveling by foot or by bike is especially associated with a lower risk of and milder depression. These results highlight the differential role of physical activity in depression.
体育活动和健康的身体成分据说可降低患重度抑郁症的风险。尽管如此，仍需要更深入了解哪种特定形式的体育活动（及其与身体成分的关系）对改善和预防抑郁症状有效。
我们比较了全球体育活动问卷中不同的自我报告体育活动以及当前患有重度抑郁发作（MDE；n = 130）的患者与健康对照者（n = 61）之间的身体成分测量值。还对这些参数与患者和对照者的抑郁严重程度及血脂水平的相关性进行了测试。
当前患有MDE的患者报告的总体育活动时间、步行或骑自行车出行时间以及休闲时的剧烈强度活动时间明显少于健康对照者。工作中剧烈强度活动时间增加、步行或骑自行车出行时间减少、体脂量增加以及瘦体重减少与更严重的抑郁严重程度显著相关。体育活动和身体测量值与血脂水平显著相关。
体育活动的自我报告、仅20天的短期随访、横断面研究设计且未考察运动的因果作用。
更多时间用于步行或骑自行车出行尤其与较低的抑郁风险和较轻的抑郁相关。这些结果突出了体育活动在抑郁症中的不同作用。
