Postsynaptic dopamine agonist properties of B-HT 920 as revealed by concomitant D-1 receptor stimulation.

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作者信息

Pifl C, Hornykiewicz O

机构信息

Institute of Biochemical Pharmacology, University of Vienna, Austria.

出版信息

Eur J Pharmacol. 1988 Jan 27;146(1):189-91. doi: 10.1016/0014-2999(88)90504-3.

DOI:10.1016/0014-2999(88)90504-3

PMID:3258244

Abstract

摘要

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Postsynaptic dopamine agonist properties of B-HT 920 as revealed by concomitant D-1 receptor stimulation.

Eur J Pharmacol. 1988 Jan 27;146(1):189-91. doi: 10.1016/0014-2999(88)90504-3.

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Climbing and stereotyped behaviours in mice require the stimulation of D-1 dopamine receptors.小鼠的攀爬行为和刻板行为需要D-1多巴胺受体的刺激。

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Is stimulation of both D1 and D2 receptors necessary for the expression of dopamine-mediated behaviors?多巴胺介导的行为表达是否需要同时刺激 D1 和 D2 受体？

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Evidence for postsynaptic dopamine agonist effects of B-HT 920 in the presence of the dopamine D-1 agonist SKF 38393.在多巴胺D-1激动剂SKF 38393存在的情况下，B-HT 920的突触后多巴胺激动剂效应的证据。

Psychopharmacology (Berl). 1988;95(3):329-32. doi: 10.1007/BF00181942.

Relative dopamine D1 and D2 receptor affinity and efficacy determine whether dopamine agonists induce hyperactivity or oral stereotypy in rats.多巴胺D1和D2受体的相对亲和力和效能决定了多巴胺激动剂是否会在大鼠中诱发多动或口部刻板行为。

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Obligatory D-1/D-2 receptor interaction in the generation of dopamine agonist related behaviors.多巴胺激动剂相关行为产生中D-1/D-2受体的强制性相互作用。

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D1 dopamine receptor activation required for postsynaptic expression of D2 agonist effects.D2激动剂效应的突触后表达需要D1多巴胺受体激活。

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Involvement of central beta-adrenoceptors in the regulation of yawning responses.

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Occurrence of yawning and decrease of prolactin levels via stimulation of dopamine D2-receptors after administration of SND 919 in rats.大鼠给予SND 919后，通过刺激多巴胺D2受体出现打哈欠现象及催乳素水平降低。

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B-HT 920 is a full agonist at both pre- and postsynaptic D-2 dopamine receptors.B-HT 920对突触前和突触后D-2多巴胺受体均为完全激动剂。

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Potentiation of yawning responses to the dopamine receptor agonists B-HT 920 and SND 919 by pindolol in the rat.吲哚洛尔对大鼠中多巴胺受体激动剂B-HT 920和SND 919引起的打哈欠反应的增强作用。

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D1/D2 dopamine and N-methyl-D-aspartate (NMDA) receptor participation in experimental catalepsy in rats.D1/D2多巴胺与N-甲基-D-天冬氨酸（NMDA）受体参与大鼠实验性僵住症

Psychopharmacology (Berl). 1992;109(4):477-83. doi: 10.1007/BF02247727.

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